@article{discovery10057056,
           title = {Study of Optimal Perimetric Testing in Children (OPTIC): evaluation of kinetic approaches in childhood neuro-ophthalmic disease},
          volume = {103},
           month = {August},
           pages = {1085--1091},
            year = {2019},
         journal = {British Journal of Ophthalmology},
          number = {8},
            note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.},
             url = {http://doi.org/10.1136/bjophthalmol-2018-312591},
        abstract = {AIMS: We compared feasibility, quality and outcomes of visual field (VF) testing in children with neuro-ophthalmic disease between the discontinued 'gold-standard' Goldmann and Octopus perimeters. METHODS: Children with neuro-ophthalmic disease, attending Great Ormond Street Hospital, London, were assessed using standardised protocols by one examiner in a single sitting, using Goldmann and Octopus kinetic perimetry. Outputs were classified to compare severity of loss and defect type. Test quality was assessed using both qualitative and quantitative methods. RESULTS: Thirty children (40\% female) aged 5-15 years participated. Goldmann perimetry was completed in full by 90.0\% vs 72.4\% for Octopus. Inability to plot the blind spot was the most common reason for not completing testing. Over 75\% completed a test in {$\leq$}20 min. Duration was similar between perimeters (paired t-test, mean difference: 0.48min (-1.2, 2.2), p=0.559). The lowest quality tests were for Octopus perimetry in children {\ensuremath{<}}8 years, without significant differences between perimeters in older children (McNemar's test, {\ensuremath{\chi}}2=1.0, p=0.317). There was broad agreement between Goldmann and Octopus outputs (good quality, n=21, Bland-Altman, mean difference for isopters I4e (-514.3  deg2 (-817.4, -211.2), p=0.814), I2e (-575.5 deg2 (-900.1, -250.9), p=0.450) and blind spot (20.8 deg2 (5.7, 35.8), p=0.451)). However, VF severity grades and defect type matched in only 57\% and 69\% of tests, respectively. Octopus perimetry underestimated severe VF defects. CONCLUSIONS: Informative perimetry is feasible in children {$\ge$}8 years with neuro-ophthalmic conditions, with either Goldmann or Octopus perimeters. However, meaningful differences exist between the two approaches with implications for consistency in longitudinal assessments.},
        keywords = {child health (paediatrics), diagnostic tests/investigation, field of vision, visual pathway},
          author = {Patel, DE and Cumberland, PM and Walters, BC and Cortina-Borja, M and Rahi, JS and OPTIC study group, {}}
}