eprintid: 10096371 rev_number: 12 eprint_status: archive userid: 608 dir: disk0/10/09/63/71 datestamp: 2020-04-27 15:49:40 lastmod: 2020-04-27 15:49:40 status_changed: 2020-04-27 15:49:40 type: article metadata_visibility: show creators_name: Hazael, R creators_name: Matsuda, S creators_name: Mori, Y creators_name: Fitzmaurice, BC creators_name: Appleby-Thomas, G creators_name: Painter, JD creators_name: Meersman, F creators_name: Richaud, M creators_name: Galas, S creators_name: Saini, NL creators_name: Ono, F creators_name: McMillan, PF title: Pressure tolerance of Artemia cysts compressed in water medium ispublished: pub divisions: UCL divisions: A01 divisions: B04 divisions: C06 divisions: F56 keywords: Artemia salina, cysts, high pressure tolerance, hatchability, osmotic pressure, ice VI phase note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: The high pressure tolerance of cysts of Artemia salina was investigated up to several GPa in water. No survival was observed after exposure to 1.0 GPa for 15 min. After exposure to 2.0 GPa for the same time duration, the hatching rate had recovered to 33%, but decreased to 8% following compression at 7.5 GPa. This contrasts with results using Fluorinert™ as the pressure-transmitting medium where 80–88% recovery was observed. The lower survival rate in water is accompanied by swelling of the eggs, indicating that liquid H2O close to the ice-VI crystallization pressure penetrated inside the eggs. This pressure exceeds the stability limit for proteins and other key biomolecules components within the embryos that could not be resuscitated. Rehydration takes several minutes and so was not completed for all samples compressed to higher pressures, prior to ice-VI formation, resulting in renewed survival. However H2O penetration inside the shell resulted in increased mortality. date: 2019-02-04 date_type: published official_url: https://doi.org/10.1080/08957959.2019.1575378 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1629820 doi: 10.1080/08957959.2019.1575378 lyricists_name: McMillan, Paul lyricists_id: PFMCM40 actors_name: Stacey, Thomas actors_id: TSSTA20 actors_role: owner full_text_status: public publication: High Pressure Research volume: 39 number: 2 pagerange: 293-300 citation: Hazael, R; Matsuda, S; Mori, Y; Fitzmaurice, BC; Appleby-Thomas, G; Painter, JD; Meersman, F; ... McMillan, PF; + view all <#> Hazael, R; Matsuda, S; Mori, Y; Fitzmaurice, BC; Appleby-Thomas, G; Painter, JD; Meersman, F; Richaud, M; Galas, S; Saini, NL; Ono, F; McMillan, PF; - view fewer <#> (2019) Pressure tolerance of Artemia cysts compressed in water medium. High Pressure Research , 39 (2) pp. 293-300. 10.1080/08957959.2019.1575378 <https://doi.org/10.1080/08957959.2019.1575378>. Green open access document_url: https://discovery-pp.ucl.ac.uk/id/eprint/10096371/1/McMillan_1.%20F%20Ono-HPR%20manuscript-revised%202019-1-18.pdf