@article{discovery10116772,
       publisher = {EUROPA EDITION},
           title = {Preclinical evaluation of a thin-strut bioresorbable scaffold (ArterioSorb)},
            year = {2020},
            note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.},
          number = {2},
          volume = {16},
           pages = {e141--e146},
         journal = {EuroIntervention},
             url = {https://doi.org/10.4244/EIJ-D-18-01190},
        abstract = {Aims: The aim of this study was to assess the acute performance of the 95 um ArterioSorb oriented poly L-lactic acid (PLLA) scaffold in comparison with the XIENCE metallic drug-eluting stent (DES) in porcine coronary arteries.

Methods and results: In 15 non-atherosclerotic Yucatan mini pigs, the ArterioSorb (3.0/14 mm) and XIENCE (3.0/15 mm) were implanted in 25 and 15 vessels, respectively. Acute performance was evaluated by using quantitative coronary angiography (QCA) and optical coherence tomography (OCT). Following three-dimensional reconstruction of the coronary arteries, endothelial shear stress (ESS) was quantified using non-Newtonian steady-flow simulation. Acute recoil measured by QCA was comparable in the two arms. Post-procedural flow and scaffold/stent area by OCT did not differ between the two devices. ESS post procedure was comparable between ArterioSorb and XIENCE (2.21{$\pm$}1.97 vs 2.25{$\pm$}1.71 Pa, p=0.314).

Conclusions: Acute recoil, luminal dimensions and ESS in the ArterioSorb oriented PLLA scaffold with thin struts of 95 um were comparable to those in the XIENCE metallic DES.},
          author = {Katagiri, Y and Torii, R and Takahashi, K and Tenekecioglu, E and Asano, T and Chichareon, P and Tomaniak, M and Piek, JJ and Wykrzykowska, JJ and Bullett, N and Ahmed, N and Al-Lamee, K and Al-Lamee, R and Leclerc, G and Kitslaar, P and Dijkstra, J and Reiber, JHC and Poon, EKW and Bourantas, C and Gijsen, F and Serruys, PW and Onuma, Y}
}