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<https://discovery-pp.ucl.ac.uk/id/eprint/10118815> <http://purl.org/dc/terms/title> "Relationship between loneliness, social isolation and modifiable risk factors for cardiovascular disease: a latent class analysis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10118815> <http://purl.org/ontology/bibo/abstract> "Background: There is growing research into the effects\r\nof psychological and social factors such as loneliness and\r\nisolation on cardiovascular disease (CVD). However, it is\r\nunclear whether individuals with particular clusters of\r\nCVD risk factors are more strongly affected by loneliness\r\nand isolation. This study aimed to identify latent\r\nclustering of modifiable risk factors among adults aged\r\n50+ and explore the relationship between loneliness,\r\nsocial isolation and risk factor patterns.\r\nMethods: Data from 8218 adults of English\r\nLongitudinal Study of Ageing were used in latent class\r\nanalyses to identify latent classes of cardiovascular risk\r\nfactors and predictors of class membership.\r\nResults: There were four latent classes: low-risk\r\n(30.2%), high-risk (15.0%), clinical-risk (42.6%) and\r\nlifestyle-risk (12.2%) classes. Loneliness was associated\r\nwith a greater risk of being in the high-risk class\r\n(relative risk ratio (RRR) 2.40, 95%CI 2.40 to 1.96) and\r\nlifestyle-risk class (RRR 1.36, 95%CI 1.10 to 1.67) and\r\na lower risk of being in the clinical-risk class (RRR 0.84,\r\n95%CI 0.72 to 0.98) relative to the low-risk class. Social\r\ndisengagement, living alone and low social contact\r\nwere also differentially associated with latent class\r\nmemberships.\r\nConclusion: These findings supplement our existing\r\nknowledge of modifiable risk factors for CVD by\r\nshowing how risk factors cluster together and how\r\nthe risk patterns are related to social factors, offering\r\nimportant implications for clinical practice and preventive\r\ninterventions"^^<http://www.w3.org/2001/XMLSchema#string> .
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