eprintid: 10118815
rev_number: 20
eprint_status: archive
userid: 608
dir: disk0/10/11/88/15
datestamp: 2021-01-11 11:13:23
lastmod: 2021-12-20 01:01:18
status_changed: 2021-01-11 11:13:23
type: article
metadata_visibility: show
creators_name: Bu, F
creators_name: Steptoe, A
creators_name: Fancourt, D
title: Relationship between loneliness, social isolation and modifiable risk factors for cardiovascular disease: a latent class analysis
ispublished: inpress
divisions: UCL
divisions: B02
divisions: D12
divisions: J96
note: This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
abstract: Background: There is growing research into the effects
of psychological and social factors such as loneliness and
isolation on cardiovascular disease (CVD). However, it is
unclear whether individuals with particular clusters of
CVD risk factors are more strongly affected by loneliness
and isolation. This study aimed to identify latent
clustering of modifiable risk factors among adults aged
50+ and explore the relationship between loneliness,
social isolation and risk factor patterns.
Methods: Data from 8218 adults of English
Longitudinal Study of Ageing were used in latent class
analyses to identify latent classes of cardiovascular risk
factors and predictors of class membership.
Results: There were four latent classes: low-risk
(30.2%), high-risk (15.0%), clinical-risk (42.6%) and
lifestyle-risk (12.2%) classes. Loneliness was associated
with a greater risk of being in the high-risk class
(relative risk ratio (RRR) 2.40, 95%CI 2.40 to 1.96) and
lifestyle-risk class (RRR 1.36, 95%CI 1.10 to 1.67) and
a lower risk of being in the clinical-risk class (RRR 0.84,
95%CI 0.72 to 0.98) relative to the low-risk class. Social
disengagement, living alone and low social contact
were also differentially associated with latent class
memberships.
Conclusion: These findings supplement our existing
knowledge of modifiable risk factors for CVD by
showing how risk factors cluster together and how
the risk patterns are related to social factors, offering
important implications for clinical practice and preventive
interventions
date: 2021-01-06
official_url: https://doi.org/10.1136/jech-2020-215539
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1841604
doi: 10.1136/jech-2020-215539
pii: jech-2020-215539
lyricists_name: Bu, Feifei
lyricists_name: Fancourt, Daisy
lyricists_name: Steptoe, Andrew
lyricists_id: FBUXX37
lyricists_id: DFANC73
lyricists_id: ASTEP39
actors_name: Bu, Feifei
actors_id: FBUXX37
actors_role: owner
full_text_status: public
publication: Journal of Epidemiology and Community Health
event_location: England
citation:        Bu, F;    Steptoe, A;    Fancourt, D;      (2021)    Relationship between loneliness, social isolation and modifiable risk factors for cardiovascular disease: a latent class analysis.                   Journal of Epidemiology and Community Health        10.1136/jech-2020-215539 <https://doi.org/10.1136/jech-2020-215539>.    (In press).    Green open access   
 
document_url: https://discovery-pp.ucl.ac.uk/id/eprint/10118815/1/jech-2020-215539.full.pdf