<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/title> "Risk of radiation-induced second malignant neoplasms from photon and proton radiotherapy in paediatric abdominal neuroblastoma"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/abstract> "Background and Purpose: State-of-the-art radiotherapy modalities have the potential of reducing late effects of treatment in childhood cancer survivors. Our aim was to investigate the carcinogenic risk associated with 3D conformal (photon) radiation (3D-CRT), intensity modulated arc therapy (IMAT) and pencil beam scanning proton therapy (PBS-PT) in the treatment of paediatric abdominal neuroblastoma.\r\n\r\nMaterials and Methods: The risk of radiation-induced second malignant neoplasm (SMN) was estimated using the concept of organ equivalent dose (OED) for eleven organs (lungs, rectum, colon, stomach, small intestine, liver, bladder, skin, central nervous system (CNS), bone, and soft tissues). The risk ratio (RR) between radiotherapy modalities and lifetime absolute risks (LAR) were reported for twenty abdominal neuroblastoma patients (median, 4y; range, 1-9y) historically treated with 3D-CRT that were also retrospectively replanned for IMAT and PBS-PT.\r\n\r\nResults: The risk of SMN due to primary radiation was reduced in PBS-PT against 3D-CRT and IMAT for most patients and organs. The RR across all organs ranged from 0.38 ± 0.22 (bladder) to 0.98 ± 0.04 (CNS) between PBS-PT and IMAT, and 0.12 ± 0.06 (rectum and bladder) to 1.06 ± 0.43 (bone) between PBS-PT and 3D-CRT. The LAR for most organs was within 0.01–1% (except the colon) with a cumulative risk of 21 ± 13%, 35 ± 14% and 35 ± 16% for PBS-PT, IMAT and 3D-CRT, respectively.\r\n\r\nConclusions: PBS-PT was associated with the lowest risk of radiation-induced SMN compared to IMAT and 3D-CRT in abdominal neuroblastoma treatment. Other clinical endpoints and plan robustness should also be considered for optimal plan selection."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/date> "2021-07-01" .
<https://discovery-pp.ucl.ac.uk/id/document/1342182> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/volume> "19" .
<https://discovery-pp.ucl.ac.uk/id/org/ext-464ff5f0fac4572c5372d3e7fc978be1> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> .
<https://discovery-pp.ucl.ac.uk/id/org/ext-464ff5f0fac4572c5372d3e7fc978be1> <http://xmlns.com/foaf/0.1/name> "Elsevier BV"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/publisher> <https://discovery-pp.ucl.ac.uk/id/org/ext-464ff5f0fac4572c5372d3e7fc978be1> .
<https://discovery-pp.ucl.ac.uk/id/publication/ext-b936e1d3271b629b35774cad5512dcdc> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery-pp.ucl.ac.uk/id/publication/ext-b936e1d3271b629b35774cad5512dcdc> <http://xmlns.com/foaf/0.1/name> "Physics and Imaging in Radiation Oncology"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/isPartOf> <https://discovery-pp.ucl.ac.uk/id/publication/ext-b936e1d3271b629b35774cad5512dcdc> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-6e78cada92f93b5c3253b76dcba1c51e> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery-pp.ucl.ac.uk/id/person/ext-6e78cada92f93b5c3253b76dcba1c51e> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-3e659b1fe7731e35376c49dedaa55c84> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery-pp.ucl.ac.uk/id/person/ext-3e659b1fe7731e35376c49dedaa55c84> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-5b7b1f6aae200b97dc994008735d0087> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery-pp.ucl.ac.uk/id/person/ext-5b7b1f6aae200b97dc994008735d0087> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-703589327a6eac5a2889afd3103b15ea> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery-pp.ucl.ac.uk/id/person/ext-703589327a6eac5a2889afd3103b15ea> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-f888429fc6e72ed7b4869943d107962b> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery-pp.ucl.ac.uk/id/person/ext-f888429fc6e72ed7b4869943d107962b> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-d1c6095291140dfd8112ae43cc928750> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery-pp.ucl.ac.uk/id/person/ext-d1c6095291140dfd8112ae43cc928750> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-106afc14c36651a66e972e5a9b46ed1f> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery-pp.ucl.ac.uk/id/person/ext-106afc14c36651a66e972e5a9b46ed1f> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-baa35714f0fe116682bb79ee3702fbde> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery-pp.ucl.ac.uk/id/person/ext-baa35714f0fe116682bb79ee3702fbde> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-01e7272c1a415cba87d073f769cf73b4> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery-pp.ucl.ac.uk/id/person/ext-01e7272c1a415cba87d073f769cf73b4> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-e92754c237729ecd171bfff4804bc02c> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery-pp.ucl.ac.uk/id/person/ext-e92754c237729ecd171bfff4804bc02c> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-f888429fc6e72ed7b4869943d107962b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-f888429fc6e72ed7b4869943d107962b> <http://xmlns.com/foaf/0.1/givenName> "W"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-f888429fc6e72ed7b4869943d107962b> <http://xmlns.com/foaf/0.1/familyName> "Harris"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-f888429fc6e72ed7b4869943d107962b> <http://xmlns.com/foaf/0.1/name> "W Harris"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-baa35714f0fe116682bb79ee3702fbde> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-baa35714f0fe116682bb79ee3702fbde> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-baa35714f0fe116682bb79ee3702fbde> <http://xmlns.com/foaf/0.1/familyName> "Gaze"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-baa35714f0fe116682bb79ee3702fbde> <http://xmlns.com/foaf/0.1/name> "M Gaze"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-703589327a6eac5a2889afd3103b15ea> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-703589327a6eac5a2889afd3103b15ea> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-703589327a6eac5a2889afd3103b15ea> <http://xmlns.com/foaf/0.1/familyName> "Alhadi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-703589327a6eac5a2889afd3103b15ea> <http://xmlns.com/foaf/0.1/name> "A Alhadi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6e78cada92f93b5c3253b76dcba1c51e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6e78cada92f93b5c3253b76dcba1c51e> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6e78cada92f93b5c3253b76dcba1c51e> <http://xmlns.com/foaf/0.1/familyName> "Taylor"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6e78cada92f93b5c3253b76dcba1c51e> <http://xmlns.com/foaf/0.1/name> "S Taylor"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-3e659b1fe7731e35376c49dedaa55c84> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-3e659b1fe7731e35376c49dedaa55c84> <http://xmlns.com/foaf/0.1/givenName> "P"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-3e659b1fe7731e35376c49dedaa55c84> <http://xmlns.com/foaf/0.1/familyName> "Lim"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-3e659b1fe7731e35376c49dedaa55c84> <http://xmlns.com/foaf/0.1/name> "P Lim"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-5b7b1f6aae200b97dc994008735d0087> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-5b7b1f6aae200b97dc994008735d0087> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-5b7b1f6aae200b97dc994008735d0087> <http://xmlns.com/foaf/0.1/familyName> "Ahmad"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-5b7b1f6aae200b97dc994008735d0087> <http://xmlns.com/foaf/0.1/name> "R Ahmad"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e92754c237729ecd171bfff4804bc02c> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e92754c237729ecd171bfff4804bc02c> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e92754c237729ecd171bfff4804bc02c> <http://xmlns.com/foaf/0.1/familyName> "Veiga"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e92754c237729ecd171bfff4804bc02c> <http://xmlns.com/foaf/0.1/name> "C Veiga"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-d1c6095291140dfd8112ae43cc928750> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-d1c6095291140dfd8112ae43cc928750> <http://xmlns.com/foaf/0.1/givenName> "V"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-d1c6095291140dfd8112ae43cc928750> <http://xmlns.com/foaf/0.1/familyName> "Rompokos"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-d1c6095291140dfd8112ae43cc928750> <http://xmlns.com/foaf/0.1/name> "V Rompokos"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-01e7272c1a415cba87d073f769cf73b4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-01e7272c1a415cba87d073f769cf73b4> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-01e7272c1a415cba87d073f769cf73b4> <http://xmlns.com/foaf/0.1/familyName> "Gains"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-01e7272c1a415cba87d073f769cf73b4> <http://xmlns.com/foaf/0.1/name> "J Gains"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-106afc14c36651a66e972e5a9b46ed1f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-106afc14c36651a66e972e5a9b46ed1f> <http://xmlns.com/foaf/0.1/givenName> "D"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-106afc14c36651a66e972e5a9b46ed1f> <http://xmlns.com/foaf/0.1/familyName> "D'Souza"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-106afc14c36651a66e972e5a9b46ed1f> <http://xmlns.com/foaf/0.1/name> "D D'Souza"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/ArticleEPrint> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/terms/isPartOf> <https://discovery-pp.ucl.ac.uk/id/repository> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://eprints.org/ontology/hasDocument> <https://discovery-pp.ucl.ac.uk/id/document/1342182> .
<https://discovery-pp.ucl.ac.uk/id/document/1342182> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery-pp.ucl.ac.uk/id/document/1342182> <http://www.w3.org/2000/01/rdf-schema#label> "Risk of radiation-induced second malignant neoplasms from photon and proton radiotherapy in paediatric abdominal neuroblastoma (Text)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://purl.org/dc/elements/1.1/hasVersion> <https://discovery-pp.ucl.ac.uk/id/document/1342182> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272> <http://eprints.org/ontology/hasPublished> <https://discovery-pp.ucl.ac.uk/id/document/1342182> .
<https://discovery-pp.ucl.ac.uk/id/document/1342182> <http://eprints.org/ontology/hasFile> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272/1/Taylor2021_PhIRO.pdf> .
<https://discovery-pp.ucl.ac.uk/id/document/1342182> <http://purl.org/dc/terms/hasPart> <https://discovery-pp.ucl.ac.uk/id/eprint/10131272/1/Taylor2021_PhIRO.pdf> .
<https://discovery-pp.ucl.ac.uk/id/eprint/10131272/1/Taylor2021_PhIRO.pdf> <http://www.w3.org/2000/01/rdf-schema#label> "Taylor2021_PhIRO.pdf"^^<http://www.w3.org/2001/XMLSchema#string> .
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