TY  - JOUR
SP  - 5872
N1  - © The Royal Society of Chemistry 2022. This article is Open Access (http://creativecommons.org/licenses/by-nc/3.0/).
EP  - 5883
PB  - Royal Society of Chemistry (RSC)
VL  - 13
AV  - public
A1  - Bolt, Robert RA
A1  - Leitch, Jamie A
A1  - Jones, Andrew C
A1  - Nicholson, William I
A1  - Browne, Duncan L
ID  - discovery10148172
UR  - https://doi.org/10.1039/D2SC01538B
JF  - Chemical Society Reviews
N2  - Rapid and wide-ranging developments have established mechanochemistry as a powerful avenue in sustainable organic synthesis. This is primarily due to unique opportunities which have been offered in solvent-free - or highly solvent-minimised - reaction systems. Nevertheless, despite elegant advances in ball-milling technology, limitations in scale-up still remain. This tutorial review covers the first reports into the translation from "batch-mode" ball-milling to "flow-mode" reactive extrusion, using twin-screw extrusion.
TI  - Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis
Y1  - 2022/05/28/
ER  -