<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> . <> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/title> "Cytoplasmic dynein heavy chain: the servant of many masters."^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/abstract> "Cytoplasmic dynein is the main retrograde motor in all eukaryotic cells. This complex comprises different subunits assembled on a cytoplasmic dynein heavy chain 1 (DYNC1H1) dimer. Cytoplasmic dynein is particularly important for neurons because it carries essential signals and organelles from distal sites to the cell body. In the past decade, several mouse models have helped to dissect the numerous functions of DYNC1H1. Additionally, several DYNC1H1 mutations have recently been found in human patients that give rise to a broad spectrum of developmental and midlife-onset disorders. Here, we discuss the effects of mutations of mouse and human DYNC1H1 and how these studies are giving us new insight into the many critical roles DYNC1H1 plays in the nervous system."^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/date> "2013-11" . <https://discovery-pp.ucl.ac.uk/id/document/59533> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/volume> "36" . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/issue> "11" . <https://discovery-pp.ucl.ac.uk/id/publication/ext-ea21652d515b4a6c9d8d859abf99a0ce> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> . <https://discovery-pp.ucl.ac.uk/id/publication/ext-ea21652d515b4a6c9d8d859abf99a0ce> <http://xmlns.com/foaf/0.1/name> "Trends Neurosci"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/isPartOf> <https://discovery-pp.ucl.ac.uk/id/publication/ext-ea21652d515b4a6c9d8d859abf99a0ce> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-f62555d677f636ed0f4ce887db8e6168> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery-pp.ucl.ac.uk/id/person/ext-f62555d677f636ed0f4ce887db8e6168> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-3a24d1d5431c1790c0ecc767d54559f8> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery-pp.ucl.ac.uk/id/person/ext-3a24d1d5431c1790c0ecc767d54559f8> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-b2228ef982ee0074d7d6546efcfa84d4> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery-pp.ucl.ac.uk/id/person/ext-b2228ef982ee0074d7d6546efcfa84d4> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-3ac4c229f22f606bc0dbefa32fb9ead7> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery-pp.ucl.ac.uk/id/person/ext-3ac4c229f22f606bc0dbefa32fb9ead7> . <https://discovery-pp.ucl.ac.uk/id/person/ext-b2228ef982ee0074d7d6546efcfa84d4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery-pp.ucl.ac.uk/id/person/ext-b2228ef982ee0074d7d6546efcfa84d4> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-b2228ef982ee0074d7d6546efcfa84d4> <http://xmlns.com/foaf/0.1/familyName> "Hafezparast"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-b2228ef982ee0074d7d6546efcfa84d4> <http://xmlns.com/foaf/0.1/name> "M Hafezparast"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3a24d1d5431c1790c0ecc767d54559f8> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3a24d1d5431c1790c0ecc767d54559f8> <http://xmlns.com/foaf/0.1/givenName> "L"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3a24d1d5431c1790c0ecc767d54559f8> <http://xmlns.com/foaf/0.1/familyName> "Greensmith"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3a24d1d5431c1790c0ecc767d54559f8> <http://xmlns.com/foaf/0.1/name> "L Greensmith"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3ac4c229f22f606bc0dbefa32fb9ead7> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3ac4c229f22f606bc0dbefa32fb9ead7> <http://xmlns.com/foaf/0.1/givenName> "EM"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3ac4c229f22f606bc0dbefa32fb9ead7> <http://xmlns.com/foaf/0.1/familyName> "Fisher"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-3ac4c229f22f606bc0dbefa32fb9ead7> <http://xmlns.com/foaf/0.1/name> "EM Fisher"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-f62555d677f636ed0f4ce887db8e6168> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery-pp.ucl.ac.uk/id/person/ext-f62555d677f636ed0f4ce887db8e6168> <http://xmlns.com/foaf/0.1/givenName> "G"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-f62555d677f636ed0f4ce887db8e6168> <http://xmlns.com/foaf/0.1/familyName> "Schiavo"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/person/ext-f62555d677f636ed0f4ce887db8e6168> <http://xmlns.com/foaf/0.1/name> "G Schiavo"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/ArticleEPrint> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://purl.org/dc/terms/isPartOf> <https://discovery-pp.ucl.ac.uk/id/repository> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://eprints.org/ontology/hasDocument> <https://discovery-pp.ucl.ac.uk/id/document/59533> . <https://discovery-pp.ucl.ac.uk/id/document/59533> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> . <https://discovery-pp.ucl.ac.uk/id/document/59533> 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(PDF)"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/document/59533> <http://eprints.org/relation/hasVolatileVersion> <https://discovery-pp.ucl.ac.uk/id/document/93435> . <https://discovery-pp.ucl.ac.uk/id/document/59533> <http://eprints.org/relation/haspreviewThumbnailVersion> <https://discovery-pp.ucl.ac.uk/id/document/93435> . <https://discovery-pp.ucl.ac.uk/id/document/59533> <http://eprints.org/relation/hasVersion> <https://discovery-pp.ucl.ac.uk/id/document/93435> . <https://discovery-pp.ucl.ac.uk/id/document/59533> <http://eprints.org/ontology/hasFile> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/1/1-s2.0-S0166223613001379-main.pdf> . <https://discovery-pp.ucl.ac.uk/id/document/59533> <http://purl.org/dc/terms/hasPart> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/1/1-s2.0-S0166223613001379-main.pdf> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/1/1-s2.0-S0166223613001379-main.pdf> <http://www.w3.org/2000/01/rdf-schema#label> "1-s2.0-S0166223613001379-main.pdf"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://eprints.org/ontology/hasDocument> <https://discovery-pp.ucl.ac.uk/id/document/93435> . <https://discovery-pp.ucl.ac.uk/id/document/93435> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> . <https://discovery-pp.ucl.ac.uk/id/document/93435> <http://www.w3.org/2000/01/rdf-schema#label> "Cytoplasmic dynein heavy chain: the servant of many masters. (Image (PNG))"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/document/93435> <http://eprints.org/relation/isVolatileVersionOf> <https://discovery-pp.ucl.ac.uk/id/document/59533> . <https://discovery-pp.ucl.ac.uk/id/document/93435> <http://eprints.org/relation/ispreviewThumbnailVersionOf> <https://discovery-pp.ucl.ac.uk/id/document/59533> . <https://discovery-pp.ucl.ac.uk/id/document/93435> <http://eprints.org/relation/isVersionOf> <https://discovery-pp.ucl.ac.uk/id/document/59533> . <https://discovery-pp.ucl.ac.uk/id/document/93435> <http://eprints.org/ontology/hasFile> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/2/preview.png> . <https://discovery-pp.ucl.ac.uk/id/document/93435> <http://purl.org/dc/terms/hasPart> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/2/preview.png> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/2/preview.png> <http://www.w3.org/2000/01/rdf-schema#label> "preview.png"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://eprints.org/ontology/hasDocument> <https://discovery-pp.ucl.ac.uk/id/document/119771> . <https://discovery-pp.ucl.ac.uk/id/document/119771> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> . <https://discovery-pp.ucl.ac.uk/id/document/119771> <http://www.w3.org/2000/01/rdf-schema#label> "Cytoplasmic dynein heavy chain: the servant of many masters. (Other)"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/document/119771> <http://eprints.org/relation/isVersionOf> <https://discovery-pp.ucl.ac.uk/id/document/59533> . <https://discovery-pp.ucl.ac.uk/id/document/119771> <http://eprints.org/relation/isVolatileVersionOf> <https://discovery-pp.ucl.ac.uk/id/document/59533> . <https://discovery-pp.ucl.ac.uk/id/document/119771> <http://eprints.org/relation/isIndexCodesVersionOf> <https://discovery-pp.ucl.ac.uk/id/document/59533> . <https://discovery-pp.ucl.ac.uk/id/document/119771> <http://eprints.org/ontology/hasFile> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/3/indexcodes.txt> . <https://discovery-pp.ucl.ac.uk/id/document/119771> <http://purl.org/dc/terms/hasPart> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/3/indexcodes.txt> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/3/indexcodes.txt> <http://www.w3.org/2000/01/rdf-schema#label> "indexcodes.txt"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> <http://www.w3.org/2000/01/rdf-schema#seeAlso> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/> . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/> <http://purl.org/dc/elements/1.1/title> "HTML Summary of #1406784 \n\nCytoplasmic dynein heavy chain: the servant of many masters.\n\n" . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/> <http://purl.org/dc/elements/1.1/format> "text/html" . <https://discovery-pp.ucl.ac.uk/id/eprint/1406784/> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery-pp.ucl.ac.uk/id/eprint/1406784> .