<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/title> "Discovery of Novel Isatin-Based p53 Inducers"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/abstract> "A series of isatin Schiff base derivatives were identified during in silico screening of the small molecule library for novel activators of p53. The compounds selected based on molecular docking results were further validated by a high-content screening assay using U2OS human osteosarcoma cells with an integrated EGFP-expressing p53-dependent reporter. The hit compounds activated and stabilized p53, as shown by Western blotting, at higher rates than the well-known positive control Nutlin-3. Thus, the p53-activating compounds identified by this approach represent useful molecular probes for various cancer studies."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/date> "2015-08-13" .
<https://discovery-pp.ucl.ac.uk/id/document/241290> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/volume> "6" .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/issue> "8" .
<https://discovery-pp.ucl.ac.uk/id/publication/ext-19485875> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery-pp.ucl.ac.uk/id/publication/ext-19485875> <http://xmlns.com/foaf/0.1/name> "ACS Medicinal Chemistry Letters"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/isPartOf> <https://discovery-pp.ucl.ac.uk/id/publication/ext-19485875> .
<https://discovery-pp.ucl.ac.uk/id/publication/ext-19485875> <http://www.w3.org/2002/07/owl#sameAs> <urn:issn:19485875> .
<https://discovery-pp.ucl.ac.uk/id/publication/ext-19485875> <http://purl.org/ontology/bibo/issn> "19485875" .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-128e93568e5852b0da1c4095783ba656> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery-pp.ucl.ac.uk/id/person/ext-128e93568e5852b0da1c4095783ba656> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-c73776d5eba7a28c06c7cf997a0529f0> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery-pp.ucl.ac.uk/id/person/ext-c73776d5eba7a28c06c7cf997a0529f0> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-309de775d1bee0ceb248cdef79d8a743> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery-pp.ucl.ac.uk/id/person/ext-309de775d1bee0ceb248cdef79d8a743> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-6116769d5dd49cbf8ff03974e7977434> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery-pp.ucl.ac.uk/id/person/ext-6116769d5dd49cbf8ff03974e7977434> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-0c31a5b503b7ee1b9adde37bb21eb663> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery-pp.ucl.ac.uk/id/person/ext-0c31a5b503b7ee1b9adde37bb21eb663> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-4227d53f16720b1f399901307f3b4d7e> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery-pp.ucl.ac.uk/id/person/ext-4227d53f16720b1f399901307f3b4d7e> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-9549e0f073e6c923e4c50a23b9362c1a> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery-pp.ucl.ac.uk/id/person/ext-9549e0f073e6c923e4c50a23b9362c1a> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-efcf9955aeabf6cd532b89621bceed10> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery-pp.ucl.ac.uk/id/person/ext-efcf9955aeabf6cd532b89621bceed10> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-416420e3c09c79a6b9f9b9441fbb8018> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery-pp.ucl.ac.uk/id/person/ext-416420e3c09c79a6b9f9b9441fbb8018> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-94de531cd5d3813ac98cd2c6a8664377> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery-pp.ucl.ac.uk/id/person/ext-94de531cd5d3813ac98cd2c6a8664377> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-e21f9c508c603041b028f3d8cac7ba9b> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery-pp.ucl.ac.uk/id/person/ext-e21f9c508c603041b028f3d8cac7ba9b> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/dc/terms/creator> <https://discovery-pp.ucl.ac.uk/id/person/ext-b03a3dcaaf74b3c73bebf92478701a0a> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://purl.org/ontology/bibo/authorList> <https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery-pp.ucl.ac.uk/id/person/ext-b03a3dcaaf74b3c73bebf92478701a0a> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-416420e3c09c79a6b9f9b9441fbb8018> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-416420e3c09c79a6b9f9b9441fbb8018> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-416420e3c09c79a6b9f9b9441fbb8018> <http://xmlns.com/foaf/0.1/familyName> "Garabadzhiu"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-416420e3c09c79a6b9f9b9441fbb8018> <http://xmlns.com/foaf/0.1/name> "A Garabadzhiu"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-94de531cd5d3813ac98cd2c6a8664377> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-94de531cd5d3813ac98cd2c6a8664377> <http://xmlns.com/foaf/0.1/givenName> "G"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-94de531cd5d3813ac98cd2c6a8664377> <http://xmlns.com/foaf/0.1/familyName> "Melino"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-94de531cd5d3813ac98cd2c6a8664377> <http://xmlns.com/foaf/0.1/name> "G Melino"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-4227d53f16720b1f399901307f3b4d7e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-4227d53f16720b1f399901307f3b4d7e> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-4227d53f16720b1f399901307f3b4d7e> <http://xmlns.com/foaf/0.1/familyName> "Smirnov"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-4227d53f16720b1f399901307f3b4d7e> <http://xmlns.com/foaf/0.1/name> "S Smirnov"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e21f9c508c603041b028f3d8cac7ba9b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e21f9c508c603041b028f3d8cac7ba9b> <http://xmlns.com/foaf/0.1/givenName> "N"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e21f9c508c603041b028f3d8cac7ba9b> <http://xmlns.com/foaf/0.1/familyName> "Barlev"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-e21f9c508c603041b028f3d8cac7ba9b> <http://xmlns.com/foaf/0.1/name> "N Barlev"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-0c31a5b503b7ee1b9adde37bb21eb663> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-0c31a5b503b7ee1b9adde37bb21eb663> <http://xmlns.com/foaf/0.1/givenName> "D"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-0c31a5b503b7ee1b9adde37bb21eb663> <http://xmlns.com/foaf/0.1/familyName> "Orlova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-0c31a5b503b7ee1b9adde37bb21eb663> <http://xmlns.com/foaf/0.1/name> "D Orlova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-309de775d1bee0ceb248cdef79d8a743> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-309de775d1bee0ceb248cdef79d8a743> <http://xmlns.com/foaf/0.1/givenName> "V"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-309de775d1bee0ceb248cdef79d8a743> <http://xmlns.com/foaf/0.1/familyName> "Petrova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-309de775d1bee0ceb248cdef79d8a743> <http://xmlns.com/foaf/0.1/name> "V Petrova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-b03a3dcaaf74b3c73bebf92478701a0a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-b03a3dcaaf74b3c73bebf92478701a0a> <http://xmlns.com/foaf/0.1/givenName> "V"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-b03a3dcaaf74b3c73bebf92478701a0a> <http://xmlns.com/foaf/0.1/familyName> "Tribulovich"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-b03a3dcaaf74b3c73bebf92478701a0a> <http://xmlns.com/foaf/0.1/name> "V Tribulovich"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-9549e0f073e6c923e4c50a23b9362c1a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-9549e0f073e6c923e4c50a23b9362c1a> <http://xmlns.com/foaf/0.1/givenName> "V"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-9549e0f073e6c923e4c50a23b9362c1a> <http://xmlns.com/foaf/0.1/familyName> "Gurzhiy"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-9549e0f073e6c923e4c50a23b9362c1a> <http://xmlns.com/foaf/0.1/name> "V Gurzhiy"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6116769d5dd49cbf8ff03974e7977434> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6116769d5dd49cbf8ff03974e7977434> <http://xmlns.com/foaf/0.1/givenName> "D"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6116769d5dd49cbf8ff03974e7977434> <http://xmlns.com/foaf/0.1/familyName> "Tentler"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-6116769d5dd49cbf8ff03974e7977434> <http://xmlns.com/foaf/0.1/name> "D Tentler"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-c73776d5eba7a28c06c7cf997a0529f0> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-c73776d5eba7a28c06c7cf997a0529f0> <http://xmlns.com/foaf/0.1/givenName> "V"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-c73776d5eba7a28c06c7cf997a0529f0> <http://xmlns.com/foaf/0.1/familyName> "Aksenova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-c73776d5eba7a28c06c7cf997a0529f0> <http://xmlns.com/foaf/0.1/name> "V Aksenova"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-efcf9955aeabf6cd532b89621bceed10> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-efcf9955aeabf6cd532b89621bceed10> <http://xmlns.com/foaf/0.1/givenName> "AL"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-efcf9955aeabf6cd532b89621bceed10> <http://xmlns.com/foaf/0.1/familyName> "Okorokov"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-efcf9955aeabf6cd532b89621bceed10> <http://xmlns.com/foaf/0.1/name> "AL Okorokov"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-128e93568e5852b0da1c4095783ba656> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-128e93568e5852b0da1c4095783ba656> <http://xmlns.com/foaf/0.1/givenName> "P"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-128e93568e5852b0da1c4095783ba656> <http://xmlns.com/foaf/0.1/familyName> "Davidovich"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/person/ext-128e93568e5852b0da1c4095783ba656> <http://xmlns.com/foaf/0.1/name> "P Davidovich"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery-pp.ucl.ac.uk/id/eprint/1492346> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> .
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