eprintid: 1570832 rev_number: 28 eprint_status: archive userid: 608 dir: disk0/01/57/08/32 datestamp: 2017-08-20 01:09:15 lastmod: 2021-10-14 22:47:05 status_changed: 2017-11-06 12:27:02 type: article metadata_visibility: show creators_name: Rando, C creators_name: Waldron, T title: Extensive periosteal new bone formation in a skeleton from post-Medieval Chichester, England: A probable case of metastatic prostatic carcinoma ispublished: pub divisions: UCL divisions: B03 divisions: C03 divisions: F31 divisions: K74 keywords: Differential diagnosis, Post-Medieval England, Neoplasm, Prostate cancer note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: An elderly male skeleton from a site in Chichester, UK, was found with a widespread periosteal reaction, principally affecting the axial skeleton and the pelvis. Radiography showed the presence of sclerosing infiltrates, mainly involving the lumbar vertebrae and pelvis. The differential diagnosis is discussed, reaching the conclusion that hypertrophic osteo-arthopathy (HOA) is the only reasonable alternative condition likely to produce such a widespread periosteal reaction as found here. HOA does not produce secondary deposits in the skeleton, however, and we conclude that his is most likely a case of prostatic carcinoma. date: 2018-06 date_type: published official_url: http://dx.doi.org/10.1016/j.ijpp.2017.07.004 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1413583 doi: 10.1016/j.ijpp.2017.07.004 lyricists_name: Rando, Carolyn lyricists_id: CJRAN72 actors_name: Dewerpe, Marie actors_id: MDDEW97 actors_role: owner full_text_status: public publication: International Journal of Paleopathology volume: 21 pagerange: 121-127 issn: 1879-9817 citation: Rando, C; Waldron, T; (2018) Extensive periosteal new bone formation in a skeleton from post-Medieval Chichester, England: A probable case of metastatic prostatic carcinoma. International Journal of Paleopathology , 21 pp. 121-127. 10.1016/j.ijpp.2017.07.004 <https://doi.org/10.1016/j.ijpp.2017.07.004>. Green open access document_url: https://discovery-pp.ucl.ac.uk/id/eprint/1570832/1/Rando_and%20Waldron%202017_Revised.pdf