Mazlin, V;
Xiao, P;
Dalimier, E;
Grieve, K;
Irsch, K;
Sahel, JA;
Fink, M;
(2018)
In vivo high resolution human corneal imaging using full-field optical coherence tomography.
Biomedical Optics Express
, 9
(2)
pp. 557-568.
10.1364/BOE.9.000557.
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Abstract
We present the first full-field optical coherence tomography (FFOCT) device capable of in vivo imaging of the human cornea. We obtained images of the epithelial structures, Bowman’s layer, sub-basal nerve plexus (SNP), anterior and posterior stromal keratocytes, stromal nerves, Descemet’s membrane and endothelial cells with visible nuclei. Images were acquired with a high lateral resolution of 1.7 µm and relatively large field-of-view of 1.26 mm x 1.26 mm – a combination, which, to the best of our knowledge, has not been possible with other in vivo human eye imaging methods. The latter together with a contactless operation, make FFOCT a promising candidate for becoming a new tool in ophthalmic diagnostics.
| Type: | Article |
|---|---|
| Title: | In vivo high resolution human corneal imaging using full-field optical coherence tomography |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/BOE.9.000557 |
| Publisher version: | http://doi.org/10.1364/BOE.9.000557 |
| Language: | English |
| Additional information: | This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10053721 |
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