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Number of items: 21.
B
Balusu, Sriram;
De Strooper, Bart;
(2024)
The necroptosis cell death pathway drives neurodegeneration in Alzheimer's disease.
Acta Neuropathologica
, 147
(1)
, Article 96. 10.1007/s00401-024-02747-5.
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D
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de Boni, Laura;
Wallis, Amber;
Hays Watson, Aurelia;
Ruiz-Riquelme, Alejandro;
Leyland, Louise-Ann;
Bourinaris, Thomas;
Hannaway, Naomi;
... Bartels, Tim; + view all
(2024)
Aggregation-resistant alpha-synuclein tetramers are reduced in the blood of Parkinson's patients.
EMBO Molecular Medicine
10.1038/s44321-024-00083-5.
(In press).
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De Strooper, Bart;
Karran, Eric;
(2024)
New precision medicine avenues to the prevention of Alzheimer's disease from insights into the structure and function of γ-secretases.
The EMBO Journal
10.1038/s44318-024-00057-w.
(In press).
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Duggan, Michael R;
Gomez, Gabriela T;
Joynes, Cassandra M;
Bilgel, Murat;
Chen, Jingsha;
Fattorelli, Nicola;
Hohman, Timothy J;
... Walker, Keenan A; + view all
(2024)
Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression.
Brain, Behavior, and Immunity
, 120
pp. 604-619.
10.1016/j.bbi.2024.07.002.
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E
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Erkert, Lena;
Gamez-Belmonte, Reyes;
Kabisch, Melanie;
Schödel, Lena;
Patankar, Jay V;
Gonzalez-Acera, Miguel;
Mahapatro, Mousumi;
... Becker, Christoph; + view all
(2024)
Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis.
Gut
10.1136/gutjnl-2023-331622.
(In press).
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G
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Giamogante, Flavia;
Barazzuol, Lucia;
Maiorca, Francesca;
Poggio, Elena;
Esposito, Alessandra;
Masato, Anna;
Napolitano, Gennaro;
... Brini, Marisa; + view all
(2024)
A SPLICS reporter reveals
-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation.
Nature Communications
, 15
, Article 1516. 10.1038/s41467-024-46007-2.
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H
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Hays Watson, Aurelia;
(2024)
The impact of lipid droplets on α-synuclein protein folding and aggregation propensities in Parkinson’s disease.
Doctoral thesis (Ph.D), UCL (University College London).
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L
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Lam, Isabel;
Ndayisaba, Alain;
Lewis, Amanda J;
Fu, YuHong;
Sagredo, Giselle T;
Kuzkina, Anastasia;
Zaccagnini, Ludovica;
... Khurana, Vikram; + view all
(2024)
Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions.
Neuron
10.1016/j.neuron.2024.06.002.
(In press).
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M
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Mallach, A;
Zielonka, M;
van Lieshout, V;
An, Y;
Khoo, JH;
Vanheusden, M;
Chen, WT;
... De Strooper, B; + view all
(2024)
Microglia-astrocyte crosstalk in the amyloid plaque niche of an Alzheimer's disease mouse model, as revealed by spatial transcriptomics.
Cell Reports
, 43
(6)
, Article 114216. 10.1016/j.celrep.2024.114216.
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Mancuso, R;
Fattorelli, N;
Martinez-Muriana, A;
Davis, E;
Wolfs, L;
Van Den Daele, J;
Geric, I;
... De Strooper, B; + view all
(2024)
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology.
Nature Neuroscience
10.1038/s41593-024-01600-y.
(In press).
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Masato, Anna;
Bubacco, Luigi;
(2024)
The αSynuclein half-life conundrum.
Neurobiology of Disease
, 196
, Article 106524. 10.1016/j.nbd.2024.106524.
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Milioto, Carmelo;
Carcolé, Mireia;
Giblin, Ashling;
Coneys, Rachel;
Attrebi, Olivia;
Ahmed, Mhoriam;
Harris, Samuel S;
... Isaacs, Adrian M; + view all
(2024)
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons.
Nature Neuroscience
10.1038/s41593-024-01589-4.
(In press).
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Mumford, Paige Soleil;
(2024)
Preclinical modelling of altered
neuroinflammation and interferon hyper-sensitivity in Alzheimer’s disease-Down syndrome.
Doctoral thesis (Ph.D), UCL (University College London).
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N
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Nazish, Iqra;
Mamais, Adamantios;
Mallach, Anna;
Bettencourt, Conceisao;
Kaganovich, Alice;
Warner, Thomas;
Hardy, John;
... Bandopadhyay, Rina; + view all
(2024)
Differential LRRK2 signalling and gene expression in WT-LRRK2 and G2019S-LRRK2 mouse microglia treated with zymosan and MLi2.
Cells
, 13
(1)
, Article 53. 10.3390/cells13010053.
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P
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Prosser, Lloyd;
(2024)
Investigating Imaging Biomarkers in Normal Ageing and Cognitive Impairment.
Doctoral thesis (Ph.D), UCL (University College London).
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S
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Schmidt, Andree;
Hrupka, Brian;
van Bebber, Frauke;
Sunil Kumar, Sanjay;
Feng, Xiao;
Tschirner, Sarah K;
Aßfalg, Marlene;
... Lichtenthaler, Stefan F; + view all
(2024)
The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling.
The Journal of Clinical Investigation
, Article e170550. 10.1172/JCI170550.
(In press).
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Scott-Solache, James;
(2024)
TREM2 signaling regulates microglial homeostatic
functions.
Doctoral thesis (Ph.D), UCL (University College London.
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Serneels, L;
Bammens, L;
Zwijsen, A;
Tolia, A;
Chávez-Gutiérrez, L;
De Strooper, B;
(2024)
Functional and topological analysis of PSENEN, the fourth subunit of the γ-secretase complex.
Journal of Biological Chemistry
, 300
(1)
, Article 105533. 10.1016/j.jbc.2023.105533.
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T
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Taddei, Raquel N;
(2024)
Understanding the role of glia and oligomeric tau in the
early synapse loss of Alzheimer disease dementia.
Doctoral thesis (Ph.D), UCL (University College London).
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V
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Vandermeulen, Lina;
Geric, Ivana;
Fumagalli, Laura;
Kreir, Mohamed;
Lu, Ashley;
Nonneman, Annelies;
Premereur, Jessie;
... Mancuso, Renzo; + view all
(2024)
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.
, Article 37. 10.1186/s13024-024-00725-9.
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Z
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Zilio, Gianluca;
Masato, Anna;
Sandre, Michelle;
Caregnato, Alberto;
Moret, Francesca;
Maciola, Agnieszka Katarzyna;
Antonini, Angelo;
... Bubacco, Luigi; + view all
(2024)
SARS-CoV-2-Mimicking Pseudoviral Particles Accelerate α-Synuclein Aggregation In Vitro.
ACS Chemical Neuroscience
, 15
(2)
pp. 215-221.
10.1021/acschemneuro.3c00468.
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