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Number of items: 21.
Article
Alibhai, J;
Blanco, RA;
Barria, MA;
Piccardo, P;
Caughey, B;
Perry, VH;
Freeman, TC;
(2016)
Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration.
PLOS Biology
, 14
(11)
, Article e1002579. 10.1371/journal.pbio.1002579.
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Chavez-Gutierrez, L;
De Strooper, B;
(2016)
Probing gamma-secretase-substrate interactions at the single amino acid residue level.
EMBO Journal
, 35
(15)
pp. 1597-1599.
10.15252/embj.201694978.
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Frigerio, CS;
De Strooper, B;
(2016)
Alzheimer's Disease Mechanisms and Emerging Roads to Novel Therapeutics.
Annual Review of Neuroscience
, 39
pp. 57-79.
10.1146/annurev-neuro-070815-014015.
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Gallardo, R;
Ramakers, M;
De Smet, F;
Claes, F;
Khodaparast, L;
Khodaparast, L;
Couceiro, JR;
... Rousseau, F; + view all
(2016)
De novo design of a biologically active amyloid.
Science
, 354
(6313)
, Article aah4949. 10.1126/science.aah4949.
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Karran, E;
De Strooper, B;
(2016)
The amyloid cascade hypothesis: are we poised for success or failure?
Journal of Neurochemistry
, 139
pp. 237-252.
10.1111/jnc.13632.
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Katsnelson, A;
De Strooper, B;
Zoghbi, HY;
(2016)
Neurodegeneration: From cellular concepts to clinical applications.
Science Translational Medicine
, 8
(364)
, Article 364ps18. 10.1126/scitranslmed.aal2074.
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Martinez-Muriana, A;
Mancuso, R;
Francos-Quijorna, I;
Olmos-Alonso, A;
Osta, R;
Perry, VH;
Navarro, X;
... Lopez-Vales, R; + view all
(2016)
CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves.
Scientific Reports
, 6
, Article 25663. 10.1038/srep25663.
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Murray, CE;
Gami, P;
Kiely, AP;
Salih, D;
Holton, J;
Lashley, T;
(2016)
Inflammatory gene expression profiles in sporadic, familial and TREM2 variant Alzheimer's disease.
Neuropathology and Applied Neurobiology
, 42
(S1)
, Article O09. 10.1111/nan.12307.
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Pigoni, M;
Wanngren, J;
Kuhn, P-H;
Munro, KM;
Gunnersen, JM;
Takeshima, H;
Feederle, R;
... Lichtenthaler, SF; + view all
(2016)
Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.
Molecular Neurodegeneration
, 11
(ARTN 67)
10.1186/s13024-016-0134-z.
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Ryan, NS;
Nicholas, JM;
Weston, PSJ;
Liang, Y;
Lashley, T;
Guerreiro, R;
Adamson, G;
... Fox, NC; + view all
(2016)
Clinical phenotype and genetic associations in autosomal dominant familial Alzheimer's disease: a case series.
LANCET NEUROLOGY
, 15
(13)
pp. 1326-1335.
10.1016/S1474-4422(16)30193-4.
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Salta, E;
Sierksma, A;
Vanden Eynden, E;
De Strooper, B;
(2016)
miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain.
EMBO Molecular Medicine
, 8
(9)
pp. 1005-1018.
10.15252/emmm.201606520.
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Sannerud, R;
Esselens, C;
Ejsmont, P;
Mattera, R;
Rochin, L;
Tharkeshwar, AK;
De Baets, G;
... Annaert, W; + view all
(2016)
Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.
Cell
, 166
(1)
pp. 193-208.
10.1016/j.cell.2016.05.020.
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Schottlaender, LV;
Bettencourt, C;
Kiely, AP;
Chalasani, A;
Neergheen, V;
Holton, JL;
Hargreaves, I;
(2016)
Coenzyme Q10 Levels Are Decreased in the Cerebellum of Multiple-System Atrophy Patients.
PLoS One
, 11
(2)
, Article e0149557. 10.1371/journal.pone.0149557.
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Soukup, S-F;
Kuenen, S;
Vanhauwaert, R;
Manetsberger, J;
Hernández-Díaz, S;
Swerts, J;
Schoovaerts, N;
... Verstreken, P; + view all
(2016)
A LRRK2-Dependent EndophilinA Phosphoswitch Is Critical for Macroautophagy at Presynaptic Terminals.
Neuron
, 92
(4)
pp. 829-844.
10.1016/j.neuron.2016.09.037.
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Spinazzi, M;
De Strooper, B;
(2016)
PARL: The mitochondrial rhomboid protease.
Seminars in Cell & Developmental Biology
, 60
pp. 19-28.
10.1016/j.semcdb.2016.07.034.
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Ungureanu, AA;
Benilova, I;
Krylychkina, O;
Braeken, D;
De Strooper, B;
Van Haesendonck, C;
Dotti, CG;
(2016)
Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons.
Scientific Reports
, 6
, Article 25841. 10.1038/srep25841.
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Vargas-Caballero, M;
Willaime-Morawek, S;
Gomez-Nicola, D;
Perry, VH;
Bulters, D;
Mudher, A;
(2016)
The use of human neurons for novel drug discovery in dementia research.
Expert Opinion on Drug Discovery
, 11
(4)
pp. 355-367.
10.1517/17460441.2016.1154528.
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Veugelen, S;
Saito, T;
Saido, TC;
Chavez-Gutierrez, L;
De Strooper, B;
(2016)
Familial Alzheimer's Disease Mutations in Presenilin Generate Amyloidogenic Ab Peptide Seeds.
Neuron
, 90
(2)
pp. 410-416.
10.1016/j.neuron.2016.03.010.
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Proceedings paper
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Kiely, A;
Murray, CE;
Asi, Y;
Ahmed, Z;
Lashley, T;
Revesz, T;
Holton, J;
(2016)
Distinct inflammatory profile in brains with multiple system atrophy.
In:
Proceedings of the 10TH FENS Forum of Neuroscience 2016.
Federation of European Neuroscience Societies (FENS): Copenhagen, Denmark.
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Murray, CE;
Gami, P;
Kiely, A;
Salih, D;
Holton, J;
Lashley, T;
(2016)
Inflammatory gene expression profile in Alzheimer's disease.
In:
Proceedings of the 49th Miami 2016 Winter Symposium.
Elsevier: Miami, FL, USA.
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Conference item
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Kiely, AP;
Murray, C;
Asi, YT;
Ahmed, Z;
Lashley, T;
Revesz, T;
Holton, JL;
(2016)
NanoString analysis of neuroinflammation in multiple system atrophy.
Presented at: 117th meeting of the British Neuropathological Society, London, UK.
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