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Number of items: 12.
Article
Aerts, L;
Miccoli, B;
Delahanty, A;
Witters, H;
Verstraelen, S;
De Strooper, B;
Braeken, D;
(2022)
Do we still need animals? Surveying the role of animal-free models in Alzheimer’s and Parkinson’s disease research.
EMBO Journal
, Article e110002. 10.15252/embj.2021110002.
(In press).
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Guo, Wenting;
Wang, Haibo;
Kumar Tharkeshwar, Arun;
Couthouis, Julien;
Braems, Elke;
Masrori, Pegah;
Van Schoor, Evelien;
... Verfaillie, Catherine; + view all
(2022)
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Alzheimer's & Dementia
10.1002/alz.12760.
(In press).
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Hardy, J;
De Strooper, B;
Escott-Price, V;
(2022)
Diabetes and Alzheimer's disease: shared genetic susceptibility?
The Lancet Neurology
, 21
(11)
pp. 962-964.
10.1016/S1474-4422(22)00395-7.
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Karran, Eric;
De Strooper, Bart;
(2022)
The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics.
Nature Reviews Drug Discovery
, 21
pp. 306-318.
10.1038/s41573-022-00391-w.
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Koper, Marta J;
Tome, Sandra O;
Gawor, Klara;
Belet, Annelies;
Van Schoor, Evelien;
Schaeverbeke, Jolien;
Vandenberghe, Rik;
... Thal, Dietmar Rudolf; + view all
(2022)
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease.
Acta Neuropathologica Communications
, 10
, Article 128. 10.1186/s40478-022-01432-6.
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Marino, Marika;
Zhou, Lujia;
Rincon, Melvin Y;
Callaerts-Vegh, Zsuzsanna;
Verhaert, Jens;
Wahis, Jérôme;
Creemers, Eline;
... Holt, Matthew G; + view all
(2022)
AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model.
EMBO Molecular Medicine
, 14
(4)
, Article e09824. 10.15252/emmm.201809824.
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Moonen, Sebastiaan;
Koper, Marta J;
Van Schoor, Evelien;
Schaeverbeke, Jolien M;
Vandenberghe, Rik;
von Arnim, Christine AF;
Tousseyn, Thomas;
... Thal, Dietmar Rudolf; + view all
(2022)
Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons.
Acta Neuropathologica
10.1007/s00401-022-02528-y.
(In press).
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Paolicelli, RC;
Sierra, A;
Stevens, B;
Tremblay, ME;
Aguzzi, A;
Ajami, B;
Amit, I;
... Wyss-Coray, T; + view all
(2022)
Microglia states and nomenclature: A field at its crossroads.
Neuron
, 110
(21)
pp. 3458-3483.
10.1016/j.neuron.2022.10.020.
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Shah, D;
Gsell, W;
Wahis, J;
Luckett, ES;
Jamoulle, T;
Vermaercke, B;
Preman, P;
... De Strooper, B; + view all
(2022)
Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer's disease.
Cell Reports
, 40
(8)
, Article 111280. 10.1016/j.celrep.2022.111280.
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Stevenson-Hoare, Joshua;
Heslegrave, Amanda;
Leonenko, Ganna;
Fathalla, Dina;
Bellou, Eftychia;
Luckcuck, Lauren;
Marshall, Rachel;
... Escott-Price, Valentina; + view all
(2022)
Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease.
Brain
10.1093/brain/awac128.
(In press).
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Wouters, Yessica;
Jaspers, Tom;
Rue, Laura;
Serneels, Lutgarde;
De Strooper, Bart;
Dewilde, Maarten;
(2022)
VHHs as tools for therapeutic protein delivery to the central nervous system.
Fluids and Barriers of the CNS
, 19
(1)
, Article 79. 10.1186/s12987-022-00374-4.
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Yshii, Lidia;
Pasciuto, Emanuela;
Bielefeld, Pascal;
Mascali, Loriana;
Lemaitre, Pierre;
Marino, Marika;
Dooley, James;
... Liston, Adrian; + view all
(2022)
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation.
Nature Immunology
, 23
pp. 878-891.
10.1038/s41590-022-01208-z.
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