da Matta Felisberto Fernandes, ML;
Kawachi, I;
Fernandes, AM;
Corrêa-Faria, P;
Paiva, SM;
Pordeus, IA;
(2016)
Oral health-related quality of life of children and teens with sickle cell disease.
Revista Brasileira de Hematologia e Hemoterapia
, 38
(2)
pp. 106-112.
10.1016/j.bjhh.2016.01.004.
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Abstract
BACKGROUND: Children with sickle cell disease may have their quality of life affected by oral alterations. However, there is still little data on oral health-related quality of life in these children. The aim of this study was to investigate the influence of sickle cell disease, socioeconomic characteristics, and oral conditions on oral health-related quality of life of children and teens. METHOD: One hundred and six children and teens with sickle cell disease were compared to a similar sample of 385 healthy peers. Data were collected through oral examinations, interviews to assess quality of life (Child Perceptions Questionnaire for children aged 8-10 and 11-14) and questionnaires containing questions on socioeconomic status. RESULTS: There were no statistically significant differences in the total scores of the Child Perceptions Questionnaires or domain scores comparing sickle cell disease patients to control subjects. When sub-scales were compared, oral symptoms and functional limitations had a greater negative impact on the quality of life of adolescents with sickle cell disease (p-value < 0.001 and p-value < 0.01, respectively) when compared to healthy controls. The only statistically significant determinants of negative impact on oral health-related quality of life in the overall sample was home overcrowding (more than two people/room) in the younger children's group, and dental malocclusion among teens. CONCLUSIONS: There was no significant difference in the negative impact on the oral health-related quality of life between the group with sickle cell disease and the control group. Of the oral alterations, there was a significant difference in the oral health-related quality of life between adolescents with sickle cell disease and controls only in relation to malocclusion. Among the socioeconomic characteristics, only overcrowding was significantly associated with a negative impact on oral health-related quality of life.
| Type: | Article |
|---|---|
| Title: | Oral health-related quality of life of children and teens with sickle cell disease |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.bjhh.2016.01.004 |
| Publisher version: | https://doi.org/10.1016/j.bjhh.2016.01.004 |
| Language: | Dutch |
| Additional information: | © 2016 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| Keywords: | Sickle cell, Quality of life, ChildOral health, Malocclusion |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10027801 |
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