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Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation

Martin, CA; Nunn, L; Lambiase, PD; (2017) Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation. Indian Pacing and Electrophysiology Journal , 17 (4) pp. 113-115. 10.1016/j.ipej.2017.05.006. Green open access

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Abstract

A young man suffered cardiac arrests with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF) triggered by ventricular premature contractions (PVCs). The arrhythmia was resistant to anti-arrhythmics, so after ICD implantation he underwent successful ablation of the triggering VE beat, which was pace-mapped to the left posterior hemi-fascicle. We review the evidence for the role of the Purkinje network in the initiation and maintenance of PVT and VF, postulating a channelopathy as a possible underlying cause, and provide recommendations for PVC ablation.

Type: Article
Title: Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ipej.2017.05.006
Publisher version: http://doi.org/10.1016/j.ipej.2017.05.006
Language: English
Additional information: Copyright © 2017, Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Ventricular fibrillation; Sudden cardiac death; Purkinje fibres; Channelopathy
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10027962
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