Almarza Novoa, E;
Kasbekar, S;
Thrasher, AJ;
Kohn, DB;
Sevilla, J;
Nguyen, T;
Schwartz, JD;
(2018)
Leukocyte adhesion deficiency-I: A comprehensive review of all published cases.
Journal of Allergy and Clinical Immunology: In Practice
, 6
(4)
1418-1420.e10.
10.1016/j.jaip.2017.12.008.
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Abstract
Leukocyte adhesion deficiency-I (LAD-I) is a rare, serious disorder with severity determined by defective CD18 expression. LAD-I is characterized by umbilical complications, granulocytosis, and diverse infections. Severe LAD-I is frequently fatal before the age of 2 years without allogeneic transplant. We identified 323 cases published between 1975 and 2017.
Type: | Article |
---|---|
Title: | Leukocyte adhesion deficiency-I: A comprehensive review of all published cases |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1016/j.jaip.2017.12.008 |
Publisher version: | http://dx.doi.org/10.1016/j.jaip.2017.12.008 |
Language: | English |
Additional information: | Copyright © 2017 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC-BY NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10042078 |
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