Fitzgerald, F;
Wing, K;
Naveed, A;
Gbessay, M;
Ross, JCG;
Checchi, F;
Youkee, D;
... Yeung, S; + view all
(2018)
Development of a pediatric ebola predictive score, Sierra Leone.
Emerging Infectious Diseases
, 24
(2)
pp. 311-319.
10.3201/eid2402.171018.
Preview |
Text
17-1018.pdf - Published Version Download (1MB) | Preview |
Abstract
We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictive (PEP) score. We collected data on all children < 13 years of age admitted to 11 Ebola holding units in Sierra Leone during August 2014-March 2015 and performed multivariable logistic regression. Among 1,054 children, 309 (29%) were EVD positive and 697 (66%) EVD negative, with 48 (5%) missing. Contact history, conjunctivitis, and age were the strongest positive predictors for EVD. The PEP score had an area under receiver operating characteristics curve of 0.80. A PEP score of 7/10 was 92% specific and 44% sensitive; 3/10 was 30% specific, 94% sensitive. The PEP score could correctly classify 79%-90% of children and could be used to facilitate triage into risk categories, depending on the sensitivity or specificity required.
Archive Staff Only
 |
View Item |
