Leonardi, A;
Doan, S;
Fauquert, JL;
Bozkurt, B;
Allegri, P;
Marmouz, F;
Rondon, C;
... Calder, V; + view all
(2017)
Diagnostic tools in ocular allergy.
Allergy
, 72
(10)
pp. 1485-1498.
10.1111/all.13178.
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Abstract
Ocular allergy (OA) includes a group of common and less frequent hypersensitivity disorders frequently misdiagnosed and not properly managed. The diagnosis of OA is usually based on clinical history and signs and symptoms, with the support of in vivo and in vitro tests when identification of the specific allergen is required. To date, no specific test is available for the diagnosis of the whole spectrum of the different forms of OA. The lack of recommendations on diagnosis of OA is considered a medical need not only for allergists but also for ophthalmologists. This position paper aims to provide a comprehensive overview of the currently available tools for diagnosing OA to promote a common nomenclature and procedures to be used by different specialists. Questionnaires, sign and symptom grading scales, tests, and potential biomarkers for OA are reviewed. We also identified several unmet needs in the diagnostic tools to generate interest, increase understanding, and inspire further investigations. Tools, recommendations, and algorithms for the diagnosis of OA are proposed for use by both allergists and ophthalmologists. Several unmet needs in the diagnostic tools should be further improved by specific clinical research in OA.
| Type: | Article |
|---|---|
| Title: | Diagnostic tools in ocular allergy |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/all.13178 |
| Publisher version: | http://doi.org/10.1111/all.13178 |
| Language: | English |
| Additional information: | © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd. This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Allergy, Immunology, allergic conjunctivitis, biomarkers, diagnosis, ocular allergy, quality of life, QUALITY-OF-LIFE, SCANNING LASER MICROSCOPY, HUMAN TEAR FLUID, VERNAL KERATOCONJUNCTIVITIS, ATOPIC KERATOCONJUNCTIVITIS, DRY EYE, CLINICAL-TRIALS, IGE DETECTION, IMPRESSION CYTOLOGY, CONFOCAL MICROSCOPY |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10043380 |
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