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Shaping Early Networks to Rule Mature Circuits: Little MiRs Go a Long Way

Marques-Smith, A; Favuzzi, E; Rico, B; (2016) Shaping Early Networks to Rule Mature Circuits: Little MiRs Go a Long Way. [Editorial comment]. Neuron , 92 (6) pp. 1154-1157. 10.1016/j.neuron.2016.12.014. Green open access

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Abstract

Normative cortical processing depends on precise interactions between excitatory and inhibitory neurons. In this issue of Neuron, Lippi et al. (2016) identify miR-101 as a master regulator coordinating molecular programs during development that ultimately impact the activity of mature networks.

Type: Article
Title: Shaping Early Networks to Rule Mature Circuits: Little MiRs Go a Long Way
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.neuron.2016.12.014
Publisher version: http://doi.org/10.1016/j.neuron.2016.12.014
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: E/I balance, microRNAs, neural circuits, development
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > The Sainsbury Wellcome Centre
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10045006
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