Jackson, C;
Southern, J;
Lalvani, A;
Drobniewski, F;
Griffiths, CJ;
Lipman, M;
Bothamley, GH;
... Abubakar, I; + view all
(2018)
Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.
Thorax
, 74
(1)
pp. 91-94.
10.1136/thoraxjnl-2017-211124.
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Abstract
We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% CIs for the relationship between diabetes mellitus (DM) and LTBI. Adjusted for age, sex, ethnicity, body mass index and the presence of other immunocompromising conditions, DM was associated with a 15% higher prevalence of LTBI (adjusted PR=1.15, 95%CI 1.02 to 1.30, p=0.025).
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