Saba, L;
Yuan, C;
Hatsukami, TS;
Balu, N;
Qiao, Y;
DeMarco, JK;
Saam, T;
... Wasserman, BA; + view all
(2018)
Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology.
American Journal of Neuroradiology
, 39
(2)
E9-E31.
10.3174/ajnr.A5488.
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Abstract
SUMMARY: Identification of carotid artery atherosclerosis is conventionally based on measurements of luminal stenosis and surface irregularities using in vivo imaging techniques including sonography, CT and MR angiography, and digital subtraction angiography. However, histopathologic studies demonstrate considerable differences between plaques with identical degrees of stenosis and indicate that certain plaque features are associated with increased risk for ischemic events. The ability to look beyond the lumen using highly developed vessel wall imaging methods to identify plaque vulnerable to disruption has prompted an active debate as to whether a paradigm shift is needed to move away from relying on measurements of luminal stenosis for gauging the risk of ischemic injury. Further evaluation in randomized clinical trials will help to better define the exact role of plaque imaging in clinical decision-making. However, current carotid vessel wall imaging techniques can be informative. The goal of this article is to present the perspective of the ASNR Vessel Wall Imaging Study Group as it relates to the current status of arterial wall imaging in carotid artery disease.
| Type: | Article |
|---|---|
| Title: | Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3174/ajnr.A5488 |
| Publisher version: | https://doi.org10.3174/ajnr.A5488 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Clinical Neurology, Neuroimaging, Radiology, Nuclear Medicine & Medical Imaging, Neurosciences & Neurology, MULTIDETECTOR-ROW CT, ATHEROSCLEROTIC PLAQUE PROGRESSION, CONTRAST-ENHANCED ULTRASOUND, TURBO SPIN-ECHO, SURFACE IRREGULARITIES CORRELATE, RISK-ASSESSMENT STRATEGIES, TRANSIENT ISCHEMIC ATTACK, FISSURED FIBROUS CAP, RICH NECROTIC CORE, IN-VIVO MRI |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10047613 |
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