Abubakar, I;
Gupta, RK;
Rangaka, MX;
Lipman, M;
(2018)
Update in Tuberculosis and Non-tuberculous Mycobacteria 2017.
Am J Respir Crit Care Med
, 197
(10)
pp. 1248-1253.
10.1164/rccm.201801-0106UP.
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Abstract
In 2016, there were an estimated 10.4 million incident cases of tuberculosis (TB) worldwide, causing 1.7 million deaths (1). Although global TB incidence and mortality rates are falling by 2% and 3% per year, respectively, these declines are far behind what is required to achieve the World Health Organization (WHO) End TB Strategy targets, which aim for 90% and 95% reductions in TB incidence and mortality, respectively, between 2015 and 2035 (2). Consequently, major advances in the understanding of TB pathogenesis (including vaccine development) and transmission, together with new tools for the diagnosis and treatment of both active TB disease and latent infection, are needed. Furthermore, the global importance of nontuberculous mycobacterial (NTM) disease is increasingly being recognized as its incidence rises (3, 4). This review summarizes the advances in both TB and NTM published in the Journal and other journals in 2017.
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