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Sterile Inflammation Fuels Gastric Cancer

Montinaro, A; Walczak, H; (2018) Sterile Inflammation Fuels Gastric Cancer. Immunity , 48 (3) pp. 481-483. 10.1016/j.immuni.2018.03.011. Green open access

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Abstract

Constitutively activated NF-κB signaling has long been known to be oncogenic. In this issue of Immunity, O’Reilly et al. (2018) unveil a link between loss of NF-κB1, aberrant STAT1 signaling, sterile inflammation, and the increased expression of immune checkpoint molecules as cancer drivers.

Type: Article
Title: Sterile Inflammation Fuels Gastric Cancer
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.immuni.2018.03.011
Publisher version: https://doi.org/10.1016/j.immuni.2018.03.011
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Immunology, NF-KAPPA-B, RISK
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Cancer Bio
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10050107
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