Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button

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Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button

Woodling, NS; Partridge, L; (2018) Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button. Neuron , 98 (6) pp. 1059-1061. 10.1016/j.neuron.2018.06.025. Green open access

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Abstract

Parkinson's disease patients report sleep disturbances well ahead of motor symptoms. In this issue of Neuron, Valadas et al. (2018) report that the disease genes pink1 and parkin exert novel, cell-type-specific effects to modulate ER-mitochondria contacts, neuropeptidergic transmission, and sleep patterns.

Type:	Article
Title:	Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button
Location:	United States
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1016/j.neuron.2018.06.025
Publisher version:	https://doi.org/10.1016/j.neuron.2018.06.025
Language:	English
Additional information:	This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords:	Drosophila, Parkin, Parkinson’s disease, Pink1, circadian rhythms, endoplasmic reticulum, mitochondria, sleep
UCL classification:	UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI:	https://discovery-pp.ucl.ac.uk/id/eprint/10051837

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