Cantarutti, C;
Raj, G;
Fogolari, F;
Giorgetti, S;
Corazza, A;
Bellotti, V;
Naumov, P;
(2018)
Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association.
Chemical Communication
, 54
(43)
pp. 5422-5425.
10.1039/c8cc01053f.
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Abstract
Protein fibrillation is involved in many serious diseases, and protein oligomers are proved to be precursors of amyloid fibrils. NMR and QCMD experiments allowed us to establish that the interaction between citrate-stabilized gold nanoparticles and a paradigmatic amyloidogenic protein, β2-microglobulin, is able to interfere with protein association into oligomers.
| Type: | Article |
|---|---|
| Title: | Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/c8cc01053f |
| Publisher version: | http://dx.doi.org/10.1039/C8CC01053F |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10052343 |
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