Xiao, P;
Mazlin, V;
Grieve, K;
Sahel, JA;
Fink, M;
Boccara, AC;
(2018)
In vivo high-resolution human retinal imaging with wavefront-correctionless full-field OCT.
Optica
, 5
(4)
pp. 409-412.
10.1364/OPTICA.5.000409.
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Abstract
As the lateral resolution of full-field optical coherence tomography (FFOCT) with spatially incoherent illumination has been shown to be insensitive to aberrations, we demonstrate high-resolution en face FFOCT retinal imaging without wavefront correction in the human eye in vivo for the first time, to our knowledge. A combination of FFOCT with spectraldomain OCT (SDOCT) is applied for real-time matching of the optical path lengths (OPLs) of FFOCT. Through the realtime cross-sectional SDOCT images, the OPL of the FFOCT reference arm is matched with different retinal layers in the FFOCT sample arm. Thus, diffraction-limited FFOCT images of multiple retinal layers are acquired at both the near periphery and the fovea. The en face FFOCT retinal images reveal information about various structures, such as the nerve fiber orientation, the blood vessel distribution, and the photoreceptor mosaic.
| Type: | Article |
|---|---|
| Title: | In vivo high-resolution human retinal imaging with wavefront-correctionless full-field OCT |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1364/OPTICA.5.000409 |
| Publisher version: | http://doi.org/10.1364/OPTICA.5.000409 |
| Language: | English |
| Additional information: | Copyright © 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions. |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10053722 |
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