Sabbah, N;
Sanda, N;
Authié, CN;
Mohand-Saïd, S;
Sahel, JA;
Habas, C;
Amedi, A;
(2017)
Reorganization of early visual cortex functional connectivity following selective peripheral and central visual loss.
Scientific Reports
, 7
, Article 43223. 10.1038/srep43223.
![[thumbnail of Published article]](https://discovery-pp.ucl.ac.uk/style/images/fileicons/text.png) |
Text (Published article)
srep43223.pdf - Published Version Download (3MB) |
Preview |
Text (Supplementary file)
srep43223-s1.pdf Download (7MB) | Preview |
Abstract
Behavioral alterations emerging after central or peripheral vision loss suggest that cerebral reorganization occurs for both the afferented and deafferented early visual cortex (EVC). We explored the functional reorganization of the central and peripheral EVC following visual field defects specifically affecting central or peripheral vision. Compared to normally sighted, afferented central and peripheral EVC enhance their functional connectivity with areas involved in visual processing, whereas deafferented central and peripheral EVC increase their functional connectivity with more remote regions. The connectivity pattern of afferented EVC suggests adaptive changes that might enhance the visual processing capacity whereas the connectivity pattern of deafferented EVC may reflect the involvement of these regions in high-order mechanisms. Characterizing and understanding the plastic changes induced by these visual defects is essential for any attempt to develop efficient rehabilitation strategies.
| Type: | Article |
|---|---|
| Title: | Reorganization of early visual cortex functional connectivity following selective peripheral and central visual loss |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/srep43223 |
| Publisher version: | https://doi.org/10.1038/srep43223 |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10053889 |
Archive Staff Only
 |
View Item |
