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Examining habituation and sensitization across repetitive laboratory stress inductions using the MAST

Quaedflieg, CWEM; Meyer, T; van Ruitenbeek, P; Smeets, T; (2017) Examining habituation and sensitization across repetitive laboratory stress inductions using the MAST. Psychoneuroendocrinology , 77 pp. 175-181. 10.1016/j.psyneuen.2016.12.009. Green open access

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Abstract

Reliably eliciting acute stress repeatedly over time is of indispensable value for research into stress vulnerability and for developing interventions aimed at increasing stress resiliency. Here, we evaluated whether the Maastricht Acute Stress Test (MAST), a potent stress protocol that combines physical and psychosocial stress components, can be used to reliably elicit subjective and neuroendocrine stress responses multiple times. Sixty healthy undergraduate participants were exposed to the MAST on three occasions, with intervals of three-weeks and one-month in between sessions. Results showed no significant signs of habituation or sensitization to the MAST in terms of subjective or physiological (salivary alpha-amylase and cortisol) stress reactivity. Fifty-nine percent of the sample displayed a significant physiological stress response (i.e., cortisol) to two MAST exposures and 57% to every MAST exposure. This study demonstrates that the MAST can be used to repeatedly induce significant stress responses.

Type: Article
Title: Examining habituation and sensitization across repetitive laboratory stress inductions using the MAST
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.psyneuen.2016.12.009
Publisher version: http://doi.org/10.1016/j.psyneuen.2016.12.009
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Repeated stress protocols; Maastricht Acute Stress Test (MAST); Stress habituation; Stress sensitization; Cortisol
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10056318
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