Miyamoto, K;
Nguyen, KT;
Allen, GE;
Jullien, J;
Kumar, D;
Otani, T;
Bradshaw, CR;
... Gurdon, JB; + view all
(2018)
Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes.
Cell Reports
, 24
(2)
pp. 304-311.
10.1016/j.celrep.2018.06.030.
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Abstract
Miyamoto et al. show genome-wide changes in chromatin accessibility during transcriptional reprogramming in oocytes using the frog nuclear transfer system. They demonstrate that donor cell chromatin states affect transcriptional reprogramming and changes in open chromatin during reprogramming are associated with specific transcription factors.
| Type: | Article |
|---|---|
| Title: | Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.celrep.2018.06.030 |
| Publisher version: | http://dx.doi.org/10.1016/j.celrep.2018.06.030 |
| Language: | English |
| Additional information: | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: | open chromatin, transcriptional activation, reprogramming, nuclear transfer |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10056812 |
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