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Methods for Enhancing the Reproducibility of Observational Research Using Electronic Health Records: Preliminary Findings From the Caliber Resource

Denaxas, S; Gonzalez-Izquierdo, A; Pikoula, M; Direk, K; Fitzpatrick, N; Hemingway, H; Smeeth, L; (2017) Methods for Enhancing the Reproducibility of Observational Research Using Electronic Health Records: Preliminary Findings From the Caliber Resource. In: Bamidis, PD and Konstantinidis, ST and Rodrigues, PP, (eds.) Proceedings of the 30th IEEE International Symposium on Computer-Based Medical Systems (IEEE CBMS). (pp. pp. 506-508). IEEE: Thessaloniki, Greece. Green open access

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Abstract

The ability of external investigators to reproduce published scientific findings is critical for the evaluation and validation of health research by the wider community. However, a substantial proportion of health research using electronic health records, data collected and generated during routine clinical care, potentially cannot reproduced. With the complexity, volume and variety of electronic health records made available for research steadily increasing, it is critical to ensure that findings from such data are reproducible and replicable by researchers. In this paper, we present some preliminary findings on how a series of methods and tools utilized in adjunct scientific disciplines can be used to enhance the reproducibility of research using electronic health records.

Type: Proceedings paper
Title: Methods for Enhancing the Reproducibility of Observational Research Using Electronic Health Records: Preliminary Findings From the Caliber Resource
Event: 30th IEEE International Symposium on Computer-Based Medical Systems (IEEE CBMS)
Location: Aristotle Univ Thessaloniki, Thessaloniki, GREECE
Dates: 22 June 2017 - 24 June 2017
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/CBMS.2017.74
Publisher version: https://doi.org/10.1109/CBMS.2017.74
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: electronic health records, reproducibility
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine > MRC Unit for Lifelong Hlth and Ageing
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics > Clinical Epidemiology
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10058730
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