Thompson, A;
(2018)
Grand perspective on tackling motor impairment.
Presented at: 34th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 2018, Berlin, Germany.
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Abstract
Motor impairment is not just about mobility, it incorporates involvement of pyramidal, extra-pyramidal and cerebellar tracts resulting to problems with strength, tone, balance, and results in difficulties with walking, sitting, transferring and upper limb function. In a condition such as multiple Sclerosis (MS), which can result in a broad range of impairments, motor dysfunction can also be aggravated by other symptoms such as cognitive impairment, mood and fatigue. Taken together this has a direct impact on a wide range of functions and activities including an increased risk of falling, activities of daily living and employment. While self-management and expert physiotherapy input are the cornerstones the management of motor impairment, there are many other treatment options addressing weakness, spasticity and ataxia. There is now a sound evidence base to support the use of slow-release fampridine to improve muscle strength and a range of interventions for spasticity with a clearer sense of the role of cannabinoids and promising studies of the role of synaptic plasticity. Targeting upper limb function, particularly in the more disabled patient, has recently become a focus of activity with the incorporation of robotics and neurophysiological interventions. As with all symptoms of MS, motor impairment requires on-going, expert input to minimise its impact on the individual.
Type: | Conference item (Presentation) |
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Title: | Grand perspective on tackling motor impairment |
Event: | 34th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) 2018 |
Location: | Berlin, Germany |
Dates: | 10th October 2018 - 12th October 2018 |
Open access status: | An open access version is available from UCL Discovery |
Publisher version: | https://doi.org/10.1177%2F1352458518798579 |
Language: | English |
Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences |
URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10062426 |
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