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Parkinson's disease treatments: focus on transcranial direct current stimulation (tDCS)

Tahtis, V; Kaski, D; (2017) Parkinson's disease treatments: focus on transcranial direct current stimulation (tDCS). Journal of Parkinsonism and Restless Legs Syndrome , 2017 (7) pp. 55-70. 10.2147/JPRLS.S128146. Green open access

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Abstract

Parkinson’s disease (PD) is among the most common progressive neurodegenerative conditions worldwide, characterized by bradykinesia, rigidity, tremor, and postural instability, in addition to a variety of cognitive and behavior complications. Current pharmacological treatment options focus on dopaminergic replacement, but these become less efficacious as the disease progresses. Noninvasive brain stimulation techniques have therefore gained favor in recent years as a means of treating the motor and non-motor complications of PD. Here we review the evidence behind the use of transcranial direct current stimulation in the treatment of motor and non-motor complications of PD, discuss the limitations that have hindered the introduction of transcranial direct current stimulation into mainstream clinical practice, and highlight future directions that may enable the translation of this research tool into clinical use.

Type: Article
Title: Parkinson's disease treatments: focus on transcranial direct current stimulation (tDCS)
Open access status: An open access version is available from UCL Discovery
DOI: 10.2147/JPRLS.S128146
Publisher version: https://doi.org/10.2147/JPRLS.S128146
Language: English
Additional information: This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License (https://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
Keywords: Parkinson’s disease, transcranial direct current stimulation, motor, cognitive, non-motor
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10063643
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