Cannioto, RA;
LaMonte, MJ;
Kelemen, LE;
Risch, HA;
Eng, KH;
Minlikeeva, AN;
Hong, C-C;
... Moysich, KB; + view all
(2016)
Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium.
British Journal of Cancer
, 115
pp. 95-101.
10.1038/bjc.2016.153.
Preview |
Text
Cannioto_bjc2016153.pdf - Published Version Download (147kB) | Preview |
Abstract
BACKGROUND: Little is known about modifiable behaviours that may be associated with epithelial ovarian cancer (EOC) survival. We conducted a pooled analysis of 12 studies from the Ovarian Cancer Association Consortium to investigate the association between pre-diagnostic physical inactivity and mortality. METHODS: Participants included 6806 women with a primary diagnosis of invasive EOC. In accordance with the Physical Activity Guidelines for Americans, women reporting no regular, weekly recreational physical activity were classified as inactive. We utilised Cox proportional hazard models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) representing the associations of inactivity with mortality censored at 5 years. RESULTS: In multivariate analysis, inactive women had significantly higher mortality risks, with (HR=1.34, 95% CI: 1.18-1.52) and without (HR=1.22, 95% CI: 1.12-1.33) further adjustment for residual disease, respectively. CONCLUSION: In this large pooled analysis, lack of recreational physical activity was associated with increased mortality among women with invasive EOC.
| Type: | Article |
|---|---|
| Title: | Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/bjc.2016.153 |
| Publisher version: | https://doi.org/10.1038/bjc.2016.153 |
| Language: | English |
| Additional information: | This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Exercise, Female, Humans, Middle Aged, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Proportional Hazards Models, Recreation, Risk Factors |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10063989 |
Archive Staff Only
 |
View Item |
