Tomkins, O;
Keddie, S;
Lunn, MP;
D'Sa, S;
(2019)
High-dose therapy and autologous transplantation for POEMS Syndrome: effective, but how to optimise?
British Journal of Haematology
, 186
(6)
e178-e181.
10.1111/bjh.16057.
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Abstract
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, skin changes) is a rare paraneoplastic phenomenon secondary to plasma cell dyscrasia. Treatment is aimed at the underlying plasma cell clone and its survival factors. Autologous stem cell transplantation (ASCT) is selected for patients who have multifocal skeletal disease and/or bone marrow involvement with adequate performance status (Dispenzieri, 2017). Because of the rarity of the disease, there are relatively few papers describing outcomes following ASCT. This analysis seeks to add further to the emerging evidence and elucidate prognostic factors.
| Type: | Article |
|---|---|
| Title: | High-dose therapy and autologous transplantation for POEMS Syndrome: effective, but how to optimise? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/bjh.16057 |
| Publisher version: | https://doi.org/10.1111/bjh.16057 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | POEMS syndrome, autologous stem cell transplantation, autologous transplantation, plasma cell dyscrasia, vascular endothelial growth factor |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10078196 |
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