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Microfluidic liquid cell chamber for scanning probe microscopy measurement application

Chin, H; Gillissen, JJJ; Miyako, E; Cho, N-J; (2019) Microfluidic liquid cell chamber for scanning probe microscopy measurement application. Review of Scientific Instruments , 90 (4) , Article 046105. 10.1063/1.5086063. Green open access

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Abstract

In this paper, we present a universal microfluidic liquid chamber device platform for atomic force microscopy (AFM), which enables to fabricate the uniform lipid bilayer on the hydrophilic surface using the solvent-assisted lipid bilayer formation method. Using this device enables us to acquire the various properties of delicate soft matter, including morphological data, and mechanical property measurements, using high-resolution AFM systems. The proposed technology is expected to provide an understanding of complicated biological materials. This work was supported by a Start-Up Grant (SUG) from Nanyang Technological University (Grant No. M4080751.070). In addition, this work was also supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI Grant-in-Aid for Scientific Research (B) (Grant No. 16H03834) and JSPS KAKENHI Fund for the Promotion of Joint International Research (Fostering Joint International Research) (Grant No. 16KK0117).

Type: Article
Title: Microfluidic liquid cell chamber for scanning probe microscopy measurement application
Open access status: An open access version is available from UCL Discovery
DOI: 10.1063/1.5086063
Publisher version: https://doi.org/10.1063/1.5086063
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Lipid bilayer, Scanning probe microscopy, Biological processes and phenomena, Atomic force microscopy, Soft matter
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10080667
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