Cornish, E;
Hudson, J;
Sayers, R;
Loveday, M;
(2020)
Improving access to contraception through integration of family planning services into a multidrug-resistant tuberculosis treatment programme.
BMJ Sexual & Reproductive Health
, 46
(2)
pp. 152-155.
10.1136/bmjsrh-2019-200400.
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Abstract
Objectives: Multidrug-resistant tuberculosis (MDR-TB) is a global public health priority. The advent of the World Health Organisation’s Short Course regimen for MDR-TB, which halves treatment duration, has transformed outcomes and treatment acceptability for affected patients. Bedaquiline, a cornerstone of the Short Course regimen, has unknown teratogenicity and the WHO therefore recommends reliable contraception for all female MDR-TB patients in order to secure eligibility for bedaquiline. We were concerned that low contraceptive uptake among female patients in our rural South African MDR-TB treatment programme could jeopardise their access to bedaquiline. We therefore conducted a service delivery improvement project that aimed to audit contraceptive use in female MDR-TB patients, integrate family planning services into MDR-TB care, and increase the proportion of female patients eligible for bedaquiline therapy. Methods: Contraceptive use and pregnancy rates were audited in all female patients aged 13–50 years initiated on our MDR-TB treatment programme in 2016. We then implemented an intervention consisting of procurement of depot-medroxyprogesterone acetate (DMPA) for the MDR-TB unit and training of specialist MDR-TB nurses in administration of DMPA. The audit cycle was repeated for all female patients aged 13–50 years initiated on the programme in January–October 2017 (post-intervention). Results: The proportion of women on injectable contraceptives by the time of MDR-TB treatment initiation increased significantly in the post-intervention cohort (77.4% vs 23.9%, p<0.0001). Conclusion: By integrating contraceptive services into our MDR-TB programme we significantly increased contraceptive uptake, protecting women from the obstetric risks associated with pregnancy during MDR-TB treatment and maximising their eligibility for bedaquiline therapy.
| Type: | Article |
|---|---|
| Title: | Improving access to contraception through integration of family planning services into a multidrug-resistant tuberculosis treatment programme |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1136/bmjsrh-2019-200400 |
| Publisher version: | http://dx.doi.org/10.1136/bmjsrh-2019-200400 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Hormonal contraception, Long-acting reversible contraception, Family planning service delivery, Multidrug-resistant tuberculosis, Human immunodeficiency virus |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10085938 |
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