Smith, M;
Meyfroidt, G;
(2017)
Critical illness: the brain is always in the line of fire.
Intensive Care Medicine
, 43
(6)
pp. 870-873.
10.1007/s00134-017-4791-3.
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Abstract
Life-threatening systemic insults or diseases often affect the brain. In critically ill patients, acute brain dysfunction manifests in several ways including reduced consciousness, coma, or delirium. The pathophysiology is complex, incompletely understood, and may relate to critical illness-related inflammatory changes, neurotransmitter imbalances, or failure of adequate energy substrate delivery [1], as well as to the applied treatments, pharmacological neurotoxicity, or the hostile ICU environment (Fig. 1) [2].
| Type: | Article |
|---|---|
| Title: | Critical illness: the brain is always in the line of fire |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s00134-017-4791-3 |
| Publisher version: | https://doi.org/10.1007/s00134-017-4791-3 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10086204 |
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