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Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial

Walsh, EI; Turner, EL; Lane, JA; Donovan, JL; Neal, DE; Hamdy, FC; Martin, RM; ... Administrative staff, .; + view all (2016) Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial. Trials , 17 , Article 497. 10.1186/s13063-016-1624-6. Green open access

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Abstract

Background: Sociodemographic characteristics are associated with participating in cancer screening and trials. We compared the characteristics of those responding with those not responding to a single invitation for prostate-specific antigen (PSA) testing for prostate cancer as part of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP). / Methods: Age, rurality and deprivation among 197,763 men from 271 cluster-randomised primary care centres in the UK were compared between those responding (n = 90,300) and those not responding (n = 100,953) to a prostate cancer testing invitation. / Results: There was little difference in age between responders and nonresponders. Responders were slightly more likely to come from urban rather than rural areas and were slightly less deprived than those who did not respond. / Conclusion: These data indicate similarities in age and only minor differences in deprivation and urban location between responders and nonresponders. These differences were smaller, but in the same direction as those observed in other screening trials. / Trial registration: ISRCTN92187251. Registered on 29 November 2004.

Type: Article
Title: Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/s13063-016-1624-6
Publisher version: https://doi.org/10.1186/s13063-016-1624-6
Language: English
Additional information: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: PSA testing, Prostate cancer, Prostate specific antigen testing, Randomised controlled trial, Screening
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10091545
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