Sleigh, JN;
(2020)
Axonal Transport: The Delivery System Keeping Nerve Cells Alive.
Frontiers for Young Minds
, 8
, Article 12. 10.3389/frym.2020.00012.
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Abstract
Cells are a little bit like cities, as they have all sorts of different cargoes that need to be constantly transported to particular destinations. This delivery process is especially important for nerve cells, because they have a long, thin tube-like structure called an axon. Nerve cells need to deliver a wide range of proteins and specialized structures up and down axons if they are to remain alive and healthy. Neurons do this using a delivery system called axonal transport. In this article, we will explore what axonal transport is and how it works. We will also discover what cargoes the nerve cells need to spread along their axons, and why this is so important for keeping nerves alive. Finally, we will look at what happens when axonal transport goes wrong and see how this may cause diseases of the nervous system.
| Type: | Article |
|---|---|
| Title: | Axonal Transport: The Delivery System Keeping Nerve Cells Alive |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.3389/frym.2020.00012 |
| Publisher version: | https://doi.org/10.3389/frym.2020.00012 |
| Language: | English |
| Additional information: | Copyright © 2020 Sleigh. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10093186 |
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