van Dongen, JA;
Langeveld, M;
van de Lande, LS;
Harmsen, MC;
Stevens, HP;
van der Lei, B;
(2019)
The Effects of Facial Lipografting on Skin Quality: A Systematic Review.
Plastic and Reconstructive Surgery
, 144
(5)
784E-797E.
10.1097/PRS.0000000000006147.
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Abstract
Background: Autologous lipografting for improvement of facial skin quality was first described by Coleman in 2006. The current dogma dictates that adipose tissue–derived stromal cells that reside in the stromal vascular fraction of lipograft contribute to skin rejuvenation (e.g., increased skin elasticity), a more homogenous skin color, and softening of skin texture. Nowadays, many studies have been reported on this “skin rejuvenation” effect of autologous fat grafting. This systematic review was undertaken to assess the efficacy of autologous lipografting on skin quality. / Methods: The MEDLINE, Embase, Cochrane Central, Web of Science, and Google Scholar databases were searched for studies evaluating the effect of autologous lipografting on facial skin quality (May 11, 2018). Outcomes of interest were skin texture, color, and elasticity in addition to histologic outcomes and number of complications. / Results: Nine studies were included, with 301 patients treated in total. No meta-analysis could be performed because of heterogeneity of the metrics and outcomes. Eight studies reported increased skin elasticity; improvement in skin texture; and a more homogeneous skin color after treatment with lipografting, cellular stromal vascular fraction, or nanofat. One study reported no increased skin elasticity after lipografting. Histologic improvement was seen after lipografting and adipose tissue–derived stromal cell injections. However, in general, the level of evidence of the included studies was low. No serious complications were reported. / Conclusion: Autologous facial lipografting and cellular stromal vascular fraction and adipose tissue–derived stromal cell injections hardly seem to improve facial skin quality but can be considered a safe procedure.
| Type: | Article |
|---|---|
| Title: | The Effects of Facial Lipografting on Skin Quality: A Systematic Review |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1097/PRS.0000000000006147 |
| Publisher version: | https://doi.org/10.1097/PRS.0000000000006147 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10093580 |
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