Christaras, D;
Pennos, A;
Ginis, H;
Artal, P;
(2018)
Effect of intraocular scattering in macular pigment optical density measurements.
Journal of Biomedical Optics
, 23
(5)
, Article 056001. 10.1117/1.JBO.23.5.056001.
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Abstract
Fundus reflectometry is a common in-vivo, noninvasive method to estimate the macular pigment optical density (MPOD). The measured density, however, can be affected by the individual’s intraocular scattering. Scattering causes a reduction in the contrast of the fundus image, which in turn leads to an underestimation of the measured density. Intraocular scattering was measured optically in a group of seven young, healthy subjects using the method of optical integration and was subsequently used to correctly estimate the MPOD from fundus images. It was shown that when scattering is not considered, the measured optical density using fundus reflectometry can be underestimated by as high as 16% for our group of subjects.
| Type: | Article |
|---|---|
| Title: | Effect of intraocular scattering in macular pigment optical density measurements |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/1.JBO.23.5.056001 |
| Publisher version: | https://doi.org/10.1117/1.JBO.23.5.056001 |
| Language: | English |
| Additional information: | © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. https://creativecommons.org/licenses/by/3.0/ |
| Keywords: | intraocular scattering; straylight; macular pigment; fundus imaging |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10094835 |
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