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The obesity epidemic – Nature via nurture: A narrative review of high-income countries

Jackson, SE; Llewellyn, CH; Smith, L; (2020) The obesity epidemic – Nature via nurture: A narrative review of high-income countries. SAGE Open Medicine , 8 (1) 10.1177/2050312120918265. Green open access

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Abstract

Over the last three decades, the prevalence of obesity has increased rapidly in populations around the world. Despite a wealth of research, the relative contributions of the different mechanisms underlying this global epidemic are not fully understood. While there is growing consensus that the rapid rise in obesity prevalence has been driven by changes to the environment, it is evident that biology plays a central role in determining who develops obesity and who remains lean in the current obesogenic environment. This review summarises evidence on the extent to which genes and the environment influence energy intake and energy expenditure, and as a result, contribute to the ongoing global obesity epidemic. The concept of genetic susceptibility to the environment driving human variation in body weight is discussed.

Type: Article
Title: The obesity epidemic – Nature via nurture: A narrative review of high-income countries
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/2050312120918265
Publisher version: https://doi.org/10.1177%2F2050312120918265
Language: English
Additional information: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Keywords: Epidemiology, public health, obesity, epidemic, gene–environment interaction, genetic influences, environmental influences, obesogenic environment
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Behavioural Science and Health
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10097367
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