Corrêa, VP;
Confortin, SC;
d’Orsi, E;
de Sá-Junior, AR;
de Oliveira, C;
Schneider, IJC;
(2020)
Depressive symptoms as an independent risk factor for mortality.
Brazilian Journal of Psychiatry
10.1590/1516-4446-2019-0749.
(In press).
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Abstract
Objective: To evaluate the relationship between presence of depressive symptoms and risk of death in older adults residing in a municipality in Southern Brazil. Methods: Between 2009 and 2014, 1,391 people participated in the EpiFloripa Aging Cohort Study, a population-based longitudinal study. Depressive symptoms were assessed through the Geriatric Depression Scale. The initial time was considered the age at the first interview, and the end time, the age at the last contact or death. Cox regression models were used to estimate the mortality risk associated with depressive symptoms, adjusted by sex, education, income, paid work, smoking status, alcohol consumption, morbidities, medication use, physical activity, disability, cognitive impairment, and body mass index. Results: The prevalence of depressive symptoms was 23.5% (95%CI 20.4-26.9). On crude analysis, the risk of mortality was 1.86 (95%CI 1.35-2.55) for individuals with depressive symptoms; in adjusted models, the risk of mortality was 1.67 (95%CI 1.15-2.40). Conclusion: Depressive symptoms are an independent risk factor for mortality in older Brazilian adults. Our findings highlight the importance of screening this population for depression and the practice of preventive actions.
| Type: | Article |
|---|---|
| Title: | Depressive symptoms as an independent risk factor for mortality |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1590/1516-4446-2019-0749 |
| Publisher version: | https://doi.org/10.1590/1516-4446-2019-0749 |
| Language: | English |
| Additional information: | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by-nc/4.0/deed.en |
| Keywords: | Depression; epidemiology; mortality; elderly |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10109261 |
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