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In vivo Time Domain Speckle Contrast Optical Spectroscopy

Pagliazzi, M; Vidal-Rosas, EE; Sekar, SKV; Di Sieno, L; Colombo, L; Contini, D; Torricelli, A; ... Durduran, T; + view all (2019) In vivo Time Domain Speckle Contrast Optical Spectroscopy. In: Dehghani, H and Wabnitz, H, (eds.) (Proceedings) Conference on Diffuse Optical Spectroscopy and Imaging VII held at European Conferences on Biomedical Optics. SPIE: Munich, Germany. Green open access

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Abstract

We propose a time domain speckle contrast optical spectroscopy (SCOS) system that makes use of a gated detector and pulsed light source to measure the blood flow variations at very short, quasi-null (<3mm) source-detector separation. We present the results of a human arm cuff occlusion and a comparison with standard SCOS, highlighting that we can probe deeper into tissue, reduce probe footprint, make efficient use of the signal and decrease cost.

Type: Proceedings paper
Title: In vivo Time Domain Speckle Contrast Optical Spectroscopy
Event: Conference on Diffuse Optical Spectroscopy and Imaging VII held at European Conferences on Biomedical Optics
Location: Munich, GERMANY
Dates: 23 June 2019 - 25 June 2019
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/12.2526651
Publisher version: https://doi.org/10.1117/12.2526651
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Technology, Physical Sciences, Engineering, Biomedical, Optics, Spectroscopy, Engineering, Time-resolved imaging, speckle imaging, spectroscopy, speckle, DIFFUSE CORRELATION SPECTROSCOPY, BLOOD-FLOW
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10111000
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