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Moving simply: Naegleria crawls and feeds using an ancient Arp2/3-dependent mechanism

Baum, B; Dey, G; (2020) Moving simply: Naegleria crawls and feeds using an ancient Arp2/3-dependent mechanism. Journal of Cell Biology , 219 (12) , Article e202009031. 10.1083/jcb.202009031. Green open access

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Abstract

Arp2/3-nucleated actin filaments drive crawling motility and phagocytosis in animal cells and slime molds. In this issue, Velle and Fritz-Laylin (2020. J. Cell Biol.https://doi.org/10.1083/jcb.202007158) now show that Naegleria gruberi, belonging to a lineage that diverged from opisthokonts around a billion years ago, uses similar mechanisms to crawl and phagocytose bacteria.

Type: Article
Title: Moving simply: Naegleria crawls and feeds using an ancient Arp2/3-dependent mechanism
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1083/jcb.202009031
Publisher version: https://doi.org/10.1083/jcb.202009031
Language: English
Additional information: Copyright © 2020 Baum and Dey. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
Keywords: Biochemistry, Cytoskeleton, Microbiology, Migration, motility
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Lab for Molecular Cell Bio MRC-UCL
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10113271
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