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Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality

Mohamed, MO; Banerjee, A; Clarke, S; De Belder, M; Patwala, A; Goodwin, AT; Kwok, CS; ... Mamas, MA; + view all (2021) Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality. European Heart Journal: Quality of Care & Clinical Outcomes , 7 (3) pp. 247-256. 10.1093/ehjqcco/qcaa079. Green open access

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Abstract

BACKGROUND: Limited data exists on the impact of COVID-19 on national changes in cardiac procedure activity, including patient characteristics and clinical outcomes before and during the COVID-19 pandemic. METHODS AND RESULTS: All major cardiac procedures (n = 374,899) performed between 1st January and 31st May for the years 2018, 2019 and 2020 were analysed, stratified by procedure type and time-period (pre-COVID: January-May 2018 and 2019 and January-February 2020 and COVID: March-May 2020). Multivariable logistic regression was performed to examine the odds ratio (OR) of 30-day mortality for procedures performed in the COVID period.Overall, there was a deficit of 45,501 procedures during the COVID period compared to the monthly averages (March-May) in 2018-2019. Cardiac catheterisation and device implantations were the most affected in terms of numbers (n = 19,637 and n = 10,453) whereas surgical procedures such as MVR, other valve replacement/repair, ASD/VSD repair and CABG were the most affected as a relative percentage difference (Δ) to previous years' averages. TAVR was the least affected (Δ-10.6%). No difference in 30-day mortality was observed between pre-COVID and COVID time-periods for all cardiac procedures except cardiac catheterisation (OR 1.25 95% confidence interval (CI) 1.07-1.47, p = 0.006) and cardiac device implantation (OR 1.35 95% CI 1.15-1.58, p < 0.001). CONCLUSION: Cardiac procedural activity has significantly declined across England during the COVID-19 pandemic, with a deficit in excess of 45000 procedures, without an increase in risk of mortality for most cardiac procedures performed during the pandemic. Major restructuring of cardiac services is necessary to deal with this deficit, which would inevitably impact long-term morbidity and mortality.

Type: Article
Title: Impact of COVID-19 on cardiac procedure activity in England and associated 30-day mortality
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/ehjqcco/qcaa079
Publisher version: https://doi.org/10.1093/ehjqcco/qcaa079
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: COVID-19, England, cardiac, mortality, procedures
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10113698
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