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Multi-spectral vascular oximetry of rat dorsal spinal cord

Ochoa-Gutierrez, V; Konda, PC; Motaghian, S; Reboud, J; Cooper, JM; Harvey, AR; (2020) Multi-spectral vascular oximetry of rat dorsal spinal cord. In: Proceedings of SPIE 11230, Optics and Biophotonics in Low-Resource Settings VI. (pp. pp. 1-4). Society of Photographic Instrumentation Engineers (SPIE) Green open access

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Abstract

We describe a visible-light multi-spectral system for vascular oximetry studies that can be implemented in lowand middle-income countries, using a low-cost electronics and optical elements, for instance a Raspberry Pi, a Pi camera under a resolution of 5-megapixel, 2592x1944-pixel resolution, and four different light sources at 480nm, 532nm, 593nm and 610nm on a singular structured illumination area. It is designed to quantify the vascular oxygen saturation change of the rat dorsal spinal cord, which uses a Phyton custom application that synchronize all elements to execute the imaging process in one system, powered by a portable rechargeable 5V battery pack. Aimed for drug discovery, tracking disease progression and understanding of progressive and degenerative diseases. By replacing expensive and bulky imaging systems.

Type: Proceedings paper
Title: Multi-spectral vascular oximetry of rat dorsal spinal cord
Event: Optics and Biophotonics in Low-Resource Settings VI
ISBN-13: 9781510632233
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/12.2558281
Publisher version: https://doi.org/10.1117/12.2558281
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Multispectral Imaging, Oximetry, Imaging System, Gradient-Index Lenses, Low-resource Settings, Biomedical Engineering
URI: https://discovery-pp.ucl.ac.uk/id/eprint/10114514
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