Porras, P;
Barrera, E;
Bridge, A;
Del-Toro, N;
Cesareni, G;
Duesbury, M;
Hermjakob, H;
... Orchard, S; + view all
(2020)
Towards a unified open access dataset of molecular interactions.
Nature Communications
, 11
, Article 6144. 10.1038/s41467-020-19942-z.
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Abstract
The International Molecular Exchange (IMEx) Consortium provides scientists with a single body of experimentally verified protein interactions curated in rich contextual detail to an internationally agreed standard. In this update to the work of the IMEx Consortium, we discuss how this initiative has been working in practice, how it has ensured database sustainability, and how it is meeting emerging annotation challenges through the introduction of new interactor types and data formats. Additionally, we provide examples of how IMEx data are being used by biomedical researchers and integrated in other bioinformatic tools and resources.
| Type: | Article |
|---|---|
| Title: | Towards a unified open access dataset of molecular interactions |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/s41467-020-19942-z |
| Publisher version: | https://doi.org/10.1038/s41467-020-19942-z |
| Language: | English |
| Additional information: | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| Keywords: | Biochemical networks, Data publication and archiving, Protein databases, Protein–protein interaction networks, Standardization |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Pre-clinical and Fundamental Science |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10116859 |
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