Buckley, J;
Shaw, P J;
Cartledge, J D;
Miller, R F;
(2002)
Multicentric plasma cell variant Castleman's disease mimicking intrapulmonary malignancy.
Sexually Transmitted Infections
, 78
(4)
pp. 304-305.
10.1136/sti.78.4.304.
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Abstract
Multicentric Castleman’s disease (CD) is an unusual B cell lymphoproliferative disorder in HIV infected individuals,1 and is caused by human herpesvirus 8. A 41 year old white homosexual man presented in December 2000 with a 3 month history of weight loss, fevers, slowly progressive cervical lymphadenopathy, and oro-cutaneous Kaposi’s sarcoma. At this time he was found to be HIV-1 antibody positive; baseline investigations showed CD4 count of 120 cells × 106/l, HIV viral load 130 000 copies/ml, Hb = 8.4 g/dl, white blood count = 2.8 × 109/l, and platelet count 118 × 109/l. A bone marrow aspirate showed a hypercellular marrow with marked dysplasia of all three cell lines. These changes were ascribed to HIV infection. A chest radiograph was normal. Antiretroviral therapy with stavudine, lamivudine, and efavirenz, and anti-pneumocystis prophylaxis with co-trimoxazole was …
| Type: | Article |
|---|---|
| Title: | Multicentric plasma cell variant Castleman's disease mimicking intrapulmonary malignancy. |
| Identifier: | PMID: 12181475 |
| Open access status: | An open access publication |
| DOI: | 10.1136/sti.78.4.304 |
| Publisher version: | http://dx.doi.org/10.1136/sti.78.4.304 |
| Language: | English |
| Additional information: | If you wish to reuse any or all of this article please use the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways. |
| URI: | https://discovery-pp.ucl.ac.uk/id/eprint/10117859 |
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